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Tbio
ZNF214
Zinc finger protein 214

Protein Summary
Description
May be involved in transcriptional regulation. This gene is expressed predominantly in the testis and encodes a zinc finger protein that contains an N-terminal kruppel-associated box A (KRABA) domain and twelve zinc finger domains. This gene is located within one of three regions on chromosome 11p15 associated with Beckwith-Wiedemann syndrome, called Beckwith-Wiedemann syndrome chromosome region-2 (BWSCR2), and is thought to play a role in the etiology of this disease. [provided by RefSeq, Aug 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000278314
  • ENSP00000278314
  • ENSG00000149050
  • ENST00000536068
  • ENSP00000445373

Symbol
  • BAZ1
  • BAZ1
  • BAZ-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.7
protein domain
0.58
tissue sample
0.45
biological process
0.41
cell line
0.41


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.54   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.54   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
USP34
Tbio
Family:  Enzyme
Novelty:  0.16444192
p_int:  0.999993592
p_ni:  0.000006408
Score:  0.256
Data Source:  BioPlex,STRINGDB
ANKS3
Tbio
Novelty:  0.19978252
p_int:  0.999991872
p_ni:  0.000008121
p_wrong:  6e-9
Score:  0.268
Data Source:  BioPlex,STRINGDB
TOPORS
Tbio
Family:  Enzyme
Novelty:  0.03910082
p_int:  0.997948034
p_ni:  0.002051965
Score:  0.554
Data Source:  BioPlex,STRINGDB
SOGA3
Tdark
Novelty:  2.17187131
p_int:  0.993007275
p_ni:  0.002690449
p_wrong:  0.004302276
Score:  0.187
Data Source:  BioPlex,STRINGDB
CENPB
Tbio
Novelty:  0.0036225
p_int:  0.989351651
p_ni:  0.010648045
p_wrong:  3.04e-7
Data Source:  BioPlex
SMARCAD1
Tbio
Novelty:  0.04117162
p_int:  0.976554361
p_ni:  0.023445633
p_wrong:  6e-9
Score:  0.214
Data Source:  BioPlex,STRINGDB
NEK7
Tchem
Family:  Kinase
Novelty:  0.02675561
p_int:  0.971224357
p_ni:  0.028744849
p_wrong:  0.000030793
Score:  0.187
Data Source:  BioPlex,STRINGDB
TRIM37
Tbio
Family:  Enzyme
Novelty:  0.02515451
p_int:  0.963591502
p_ni:  0.016832843
p_wrong:  0.019575655
Score:  0.205
Data Source:  BioPlex,STRINGDB
LRP4
Tbio
Novelty:  0.01336125
p_int:  0.846392903
p_ni:  0.153600685
p_wrong:  0.000006411
Score:  0.162
Data Source:  BioPlex,STRINGDB
TRIM39
Tbio
Family:  Enzyme
Novelty:  0.0837441
p_int:  0.831412662
p_ni:  0.167481847
p_wrong:  0.001105491
Score:  0.173
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

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Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
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Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 214
VGNC:934
466422
Macaque
zinc finger protein 214
708389
Dog
zinc finger protein 214
VGNC:52859
485363
Horse
zinc finger protein 214
VGNC:49298
100070494
Cow
zinc finger protein 214
VGNC:49994
100140999
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 214
Macaque
zinc finger protein 214
Dog
zinc finger protein 214
Horse
zinc finger protein 214
Cow
zinc finger protein 214
Publication Statistics
PubMed Score 6.54
PubMed score by year
PubTator Score 6.95
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title