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Tdark
TMEM31
Transmembrane protein 31

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319560
  • ENSP00000316940
  • ENSG00000179363
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.48
chemical
0.41
cellular component
0.38
cell line
0.36
virus perturbation
0.28


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (61)
VPS13D
Tdark
Novelty:  0.12578583
p_int:  0.999999975
p_ni:  2.5e-8
Data Source:  BioPlex
ZRANB1
Tbio
Family:  Enzyme
Novelty:  0.07721072
p_int:  0.999998043
p_ni:  8.51e-7
p_wrong:  0.000001106
Data Source:  BioPlex
ATXN3
Tbio
Novelty:  0.00201109
p_int:  0.999992214
p_ni:  0.000005918
p_wrong:  0.000001868
Data Source:  BioPlex
CCDC92
Tbio
Novelty:  0.32125749
p_int:  0.999971713
p_ni:  0.000028267
p_wrong:  2.1e-8
Data Source:  BioPlex
UBB
Tbio
Novelty:  0.00661254
p_int:  0.999939253
p_ni:  0.000060565
p_wrong:  1.82e-7
Data Source:  BioPlex
UBQLN1
Tbio
Novelty:  0.00921991
p_int:  0.999936835
p_ni:  0.000063165
Data Source:  BioPlex
USP36
Tbio
Family:  Enzyme
Novelty:  0.02779727
p_int:  0.999934651
p_ni:  0.000064788
p_wrong:  5.6e-7
Data Source:  BioPlex
RAP1A
Tchem
Family:  Enzyme
Novelty:  0.00375413
p_int:  0.999934622
p_ni:  0.000044795
p_wrong:  0.000020583
Data Source:  BioPlex
VPS13C
Tbio
Novelty:  0.05207291
p_int:  0.999862368
p_ni:  0.000137632
Data Source:  BioPlex
UBXN7
Tbio
Novelty:  0.07437638
p_int:  0.999725926
p_ni:  0.000271863
p_wrong:  0.00000221
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
47.7
lymphocyte percentage of leukocytes
1
1
1
12.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
47.7
lymphocyte percentage of leukocytes
1
12.1
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 31
VGNC:11615
100615834
Macaque
transmembrane protein 31
100429773
Dog
transmembrane protein 31 [Source:HGNC Symbol;Acc:HGNC:28601]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 31
Macaque
transmembrane protein 31
Dog
transmembrane protein 31 [Source:HGNC Symbol;Acc:HGNC:28601]
Publication Statistics
PubMed Score 1.74
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title