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Tdark
TIGD5
Tigger transposable element-derived protein 5

Protein Summary
Description
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321385
  • ENSP00000315906
  • ENSG00000278016
  • ENST00000504548
  • ENSP00000421489
  • ENSG00000179886
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.8
transcription factor binding site profile
0.75
cell line
0.65
tissue sample
0.64
protein domain
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.83   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 32   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.83   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (64)
P4HA2
Tbio
Family:  Enzyme
Novelty:  0.02097718
p_int:  0.999920565
p_ni:  0.000079404
p_wrong:  3.2e-8
Data Source:  BioPlex
P4HA1
Tchem
Family:  Enzyme
Novelty:  0.01624726
p_int:  0.999799079
p_ni:  0.00020092
Data Source:  BioPlex
MAGEA4
Tbio
Novelty:  0.00949096
p_int:  0.99975571
p_ni:  0.00024429
Score:  0.224
Data Source:  BioPlex,STRINGDB
PRMT2
Tbio
Family:  Epigenetic
Novelty:  0.04121581
p_int:  0.999147855
p_ni:  0.000852145
Data Source:  BioPlex
ZMYND19
Tdark
Novelty:  0.3590069
p_int:  0.999138971
p_ni:  0.000861029
Score:  0.15
Data Source:  BioPlex,STRINGDB
GID4
Tbio
Novelty:  0.05252674
p_int:  0.998781563
p_ni:  0.001218437
Data Source:  BioPlex
ARMC8
Tbio
Novelty:  0.06820746
p_int:  0.998336953
p_ni:  0.001663047
Data Source:  BioPlex
MFAP4
Tbio
Novelty:  0.02023782
p_int:  0.998291173
p_ni:  0.001708825
p_wrong:  1e-9
Data Source:  BioPlex
P4HA3
Tbio
Family:  Enzyme
Novelty:  0.03832564
p_int:  0.997557208
p_ni:  0.002442792
Data Source:  BioPlex
P3H1
Tbio
Family:  Enzyme
Novelty:  0.02067711
p_int:  0.997475227
p_ni:  0.002524773
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (18)
Items per page:
1 – 5 of 18
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
2
3
92.3
red blood cell distribution width
3
2
3
92.3
metabolite measurement
1
1
1
82.8
metabolite measurement
1
1
1
82.8
C-reactive protein measurement
2
2
2
75.9
Items per page:
1 – 5 of 18
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
92.3
red blood cell distribution width
3
92.3
metabolite measurement
1
82.8
metabolite measurement
1
82.8
C-reactive protein measurement
2
75.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
tigger transposable element derived 5
709184
Mouse
MGI:2145902
105734
Rat
RGD:1311576
300034
Dog
tigger transposable element derived 5
VGNC:47372
100855621
Cow
tigger transposable element derived 5
VGNC:35867
101903505
Species
Name
OMA
EggNOG
Inparanoid
Macaque
tigger transposable element derived 5
Mouse
Rat
Dog
tigger transposable element derived 5
Cow
tigger transposable element derived 5
Publication Statistics
PubMed Score 0.83
PubMed score by year
PubTator Score 0.26
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title