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Tdark
SSX7
Protein SSX7

Protein Summary
Description
Could act as a modulator of transcription. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298181
  • ENSP00000298181
  • ENSG00000187754
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.58
cell line
0.51
microRNA
0.51
tissue
0.47
biological process
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.14   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.14   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
SSX2
Tbio
Novelty:  0.00227167
p_int:  0.999999999
p_wrong:  1e-9
Score:  0.877
Data Source:  BioPlex,STRINGDB
SSX3
Tdark
Novelty:  0.2308992
p_int:  0.984403422
p_ni:  0.000001254
p_wrong:  0.015595324
Score:  0.933
Data Source:  BioPlex,STRINGDB
SPANXN1
Tdark
Novelty:  0.73238174
Score:  0.669
Data Source:  STRINGDB
SPANXN2
Tdark
Novelty:  1.59501259
Score:  0.63
Data Source:  STRINGDB
MAGEB4
Tdark
Novelty:  0.2709865
Score:  0.602
Data Source:  STRINGDB
MAGEB6
Tdark
Novelty:  1.14058608
Score:  0.601
Data Source:  STRINGDB
SPANXN3
Tdark
Novelty:  4.06770018
Score:  0.589
Data Source:  STRINGDB
SPANXN4
Tdark
Novelty:  1.91062423
Score:  0.588
Data Source:  STRINGDB
XAGE3
Tdark
Novelty:  0.1418603
Score:  0.557
Data Source:  STRINGDB
OIP5
Tbio
Novelty:  0.02546471
Score:  0.539
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
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GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.14
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title