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Tdark
SLC35F5
Solute carrier family 35 member F5

Protein Summary
Description
Putative solute transporter.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000245680
  • ENSP00000245680
  • ENSG00000115084

Symbol
  • NS5ATP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.84
transcription factor perturbation
0.84
transcription factor binding site profile
0.81
histone modification site profile
0.79
disease perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.91   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.91   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
MANSC1
Tdark
Novelty:  0.91681036
p_int:  0.99946332
p_ni:  0.000536544
p_wrong:  1.36e-7
Data Source:  BioPlex
CTLA4
Tclin
Novelty:  0.00012781
p_int:  0.99895855
p_ni:  0.000761534
p_wrong:  0.000279916
Data Source:  BioPlex
SPINT2
Tbio
Family:  Enzyme
Novelty:  0.0046602
p_int:  0.984233379
p_ni:  0.003679388
p_wrong:  0.012087234
Data Source:  BioPlex
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.965067037
p_ni:  0.013574943
p_wrong:  0.021358019
Data Source:  BioPlex
C3AR1
Tchem
Family:  GPCR
Novelty:  0.00527301
p_int:  0.956837322
p_ni:  0.008118873
p_wrong:  0.035043805
Data Source:  BioPlex
GINM1
Tdark
Novelty:  1.0701107
p_int:  0.949162683
p_ni:  0.045652274
p_wrong:  0.005185043
Score:  0.167
Data Source:  BioPlex,STRINGDB
SLC22A9
Tbio
Family:  Transporter
Novelty:  0.02212992
p_int:  0.896628386
p_ni:  0.00593739
p_wrong:  0.097434224
Score:  0.435
Data Source:  BioPlex,STRINGDB
IL17RB
Tbio
Novelty:  0.01540031
p_int:  0.83806132
p_ni:  0.006210036
p_wrong:  0.155728644
Score:  0.177
Data Source:  BioPlex,STRINGDB
SHOC2
Tbio
Novelty:  0.01203957
Score:  0.624
Data Source:  STRINGDB
PLCL2
Tbio
Family:  Enzyme
Novelty:  0.13454277
Score:  0.617
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
2
3
3
69.8
waist-hip ratio
2
5
5
61.8
BMI-adjusted waist circumference
1
2
2
37.3
sex hormone-binding globulin measurement
1
1
1
6.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
3
69.8
waist-hip ratio
5
61.8
BMI-adjusted waist circumference
2
37.3
sex hormone-binding globulin measurement
1
6.7
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member F5
VGNC:9058
459562
Macaque
solute carrier family 35 member F5
709750
Mouse
MGI:1921400
74150
Rat
RGD:1308125
288993
Dog
solute carrier family 35 member F5
VGNC:46379
476123
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member F5
Macaque
solute carrier family 35 member F5
Mouse
Rat
Dog
solute carrier family 35 member F5
Publication Statistics
PubMed Score 1.91
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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PMID
Year
Title