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Tdark
SLC17A2
Sodium-dependent phosphate transport protein 3

Protein Summary
Description
May be involved in actively transporting phosphate into cells via Na(+) cotransport.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265425
  • ENSP00000265425
  • ENSG00000112337
  • ENST00000360488
  • ENSP00000353677
  • ENST00000377850
  • ENSP00000367081

Symbol
  • NPT3
  • NPT3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.7
molecular function
0.7
small molecule perturbation
0.57
gene perturbation
0.53
cell line
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.08   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 85   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.08   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 85   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (80)
LRRC8D
Tbio
Novelty:  0.10536285
p_int:  0.999945476
p_ni:  0.000052175
p_wrong:  0.000002348
Score:  0.175
Data Source:  BioPlex,STRINGDB
KCNT2
Tchem
Family:  IC
Novelty:  0.02412039
p_int:  0.999833261
p_ni:  0.000166739
Data Source:  BioPlex
UBB
Tbio
Novelty:  0.00661254
p_int:  0.999788218
p_ni:  0.000211782
Data Source:  BioPlex
ABCD4
Tbio
Family:  Transporter
Novelty:  0.04096359
p_int:  0.999647731
p_ni:  0.000352268
p_wrong:  1e-9
Score:  0.187
Data Source:  BioPlex,STRINGDB
ANO10
Tbio
Novelty:  0.03373977
p_int:  0.999571283
p_ni:  0.000001003
p_wrong:  0.000427713
Score:  0.288
Data Source:  BioPlex,STRINGDB
ABCB9
Tbio
Family:  Transporter
Novelty:  0.02217672
p_int:  0.999563201
p_ni:  0.00043626
p_wrong:  5.38e-7
Score:  0.159
Data Source:  BioPlex,STRINGDB
TAP2
Tbio
Novelty:  0.0390555
p_int:  0.999212279
p_ni:  0.000787627
p_wrong:  9.3e-8
Score:  0.167
Data Source:  BioPlex,STRINGDB
SARAF
Tbio
Novelty:  0.0383833
p_int:  0.997049531
p_ni:  0.002950467
p_wrong:  2e-9
Data Source:  BioPlex
ABCC10
Tbio
Family:  Transporter
Novelty:  0.02281831
p_int:  0.996801953
p_ni:  0.003173292
p_wrong:  0.000024755
Score:  0.157
Data Source:  BioPlex,STRINGDB
SLC16A13
Tbio
Family:  Transporter
Novelty:  0.15843384
p_int:  0.994843453
p_ni:  0.003167287
p_wrong:  0.001989261
Score:  0.159
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (431)
Find Similar Targets
Items per page:
1 – 5 of 431
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Osteoblast Signaling
WikiPathways
Butyrate-induced histone acetylation
WikiPathways
Butyrate-induced histone acetylation
WikiPathways
Nicotine Metabolism
WikiPathways
Nicotine Metabolism
Name
Explore in Pharos
Explore in Source
Osteoblast Signaling
Butyrate-induced histone acetylation
Butyrate-induced histone acetylation
Nicotine Metabolism
Nicotine Metabolism
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (28)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
5
3
4
6.2
98
uric acid measurement
3
3
4
96.8
urinary metabolite measurement
1
3
4
86.3
erythrocyte measurement
1
1
1
86
2
2
0
1.2
84.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
4
6.2
98
uric acid measurement
4
96.8
urinary metabolite measurement
4
86.3
erythrocyte measurement
1
86
0
1.2
84.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 17 member 2
VGNC:7912
471872
Macaque
solute carrier family 17 member 2
719411
Mouse
MGI:2443098
218103
Rat
RGD:1308821
306950
Dog
solute carrier family 17 member 2
VGNC:46249
488255
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 17 member 2
Macaque
solute carrier family 17 member 2
Mouse
Rat
Dog
solute carrier family 17 member 2
Publication Statistics
PubMed Score 3.08
PubMed score by year
PubTator Score 4.38
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title