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Tdark
SFT2D2
Vesicle transport protein SFT2B

Protein Summary
Description
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000271375
  • ENSP00000271375
  • ENSG00000213064

Symbol
  • UNQ512
  • dJ747L4.C1.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
interacting protein
0.7
histone modification site profile
0.69
disease perturbation
0.68
tissue sample
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.13   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 151   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.13   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 151   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
ORMDL1
Tbio
Novelty:  0.1323746
Score:  0.764
Data Source:  STRINGDB
LACTB2
Tbio
Family:  Enzyme
Novelty:  0.1868172
Score:  0.692
Data Source:  STRINGDB
OR11L1
Tdark
Family:  oGPCR
Novelty:  2.63771662
Score:  0.656
Data Source:  STRINGDB
STX5
Tbio
Novelty:  0.00964918
Score:  0.606
Data Source:  STRINGDB
TBX19
Tbio
Family:  TF
Novelty:  0.01599679
Score:  0.603
Data Source:  STRINGDB
ZDHHC13
Tbio
Family:  Enzyme
Novelty:  0.17442533
Score:  0.59
Data Source:  STRINGDB
HARBI1
Tbio
Family:  Enzyme
Novelty:  0.22704408
Score:  0.573
Data Source:  STRINGDB
HRASLS
Tbio
Novelty:  0.11804852
Score:  0.553
Data Source:  STRINGDB
VASN
Tbio
Novelty:  0.05424159
Score:  0.551
Data Source:  STRINGDB
OR14A16
Tdark
Family:  oGPCR
Novelty:  2.6836052
Score:  0.533
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
3
3
81.5
leukocyte count
1
1
1
27.4
testosterone measurement
4
1
3
6.3
13.2
HbA1c measurement
1
1
1
5.4
hemoglobin A1 measurement
1
1
1
1.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
81.5
leukocyte count
1
27.4
testosterone measurement
3
6.3
13.2
HbA1c measurement
1
5.4
hemoglobin A1 measurement
1
1.4
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SFT2 domain containing 2
VGNC:1544
100613333
Mouse
MGI:1917362
108735
Rat
RGD:1310623
360868
Dog
SFT2 domain containing 2
VGNC:53831
490357
Horse
SFT2 domain containing 2
VGNC:22902
100630191
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SFT2 domain containing 2
Mouse
Rat
Dog
SFT2 domain containing 2
Horse
SFT2 domain containing 2
Publication Statistics
PubMed Score 1.13
PubMed score by year
PubTator Score 0.57
PubTator score by year
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Related Publications
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PMID
Year
Title