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Tdark
SERTAD4
SERTA domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367012
  • ENSP00000355979
  • ENSG00000082497
  • ENST00000630425
  • ENSP00000486369
  • ENSG00000281230

Symbol
  • DJ667H12.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
gene perturbation
0.81
small molecule perturbation
0.79
disease
0.74
PubMedID
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
PPP2R2D
Tbio
Family:  Enzyme
Novelty:  0.0658328
p_int:  0.999999792
p_ni:  2.08e-7
Score:  0.668
Data Source:  BioPlex,STRINGDB
PPP2R2C
Tbio
Family:  Enzyme
Novelty:  0.05453128
p_int:  0.999998485
p_ni:  0.000001044
p_wrong:  4.71e-7
Score:  0.747
Data Source:  BioPlex,STRINGDB
ZFP1
Tbio
Family:  TF
Novelty:  0.02526416
p_int:  0.999995438
p_ni:  0.00000451
p_wrong:  5.2e-8
Score:  0.234
Data Source:  BioPlex,STRINGDB
PPP2CA
Tchem
Family:  Enzyme
Novelty:  0.00496839
p_int:  0.999879879
p_ni:  0.000120121
Score:  0.669
Data Source:  BioPlex,STRINGDB
PPP2R1B
Tbio
Family:  Enzyme
Novelty:  0.03936638
p_int:  0.99984004
p_ni:  0.00015996
Score:  0.68
Data Source:  BioPlex,STRINGDB
CBLL2
Tdark
Family:  Enzyme
Novelty:  0.27990611
p_int:  0.999722634
p_ni:  3.86e-7
p_wrong:  0.00027698
Score:  0.703
Data Source:  BioPlex,STRINGDB
CRY2
Tbio
Novelty:  0.00156961
p_int:  0.999146985
p_ni:  0.000001682
p_wrong:  0.000851333
Data Source:  BioPlex
PPP2R2A
Tchem
Family:  Enzyme
Novelty:  0.01723628
p_int:  0.978043761
p_ni:  0.021956239
Score:  0.748
Data Source:  BioPlex,STRINGDB
POTEF
Tbio
Novelty:  0.00191599
p_int:  0.975821707
p_ni:  0.024178293
Data Source:  BioPlex
PPP2R1A
Tbio
Family:  Enzyme
Novelty:  0.01134139
p_int:  0.957685038
p_ni:  0.042314962
Score:  0.807
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at first birth measurement
1
1
1
40.7
smoking initiation
2
2
2
37.6
heel bone mineral density
3
1
3
28
body height
1
1
1
11.3
smoking behavior
1
1
1
2.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at first birth measurement
1
40.7
smoking initiation
2
37.6
heel bone mineral density
3
28
body height
1
11.3
smoking behavior
1
2.1
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SERTA domain containing 4
457704
Macaque
SERTA domain containing 4
712616
Mouse
MGI:2443496
214791
Rat
RGD:1565408
360899
Dog
SERTA domain containing 4
VGNC:46045
490276
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SERTA domain containing 4
Macaque
SERTA domain containing 4
Mouse
Rat
Dog
SERTA domain containing 4
Publication Statistics
PubMed Score 1.21
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title