Protein Summary
- ENST00000312838
- ENSP00000326095
- ENSG00000158717
- ENST00000537718
- ENSP00000446301
- ENST00000541206
- ENSP00000440454
- ENST00000567844
- ENSP00000457336
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.81 | ||
disease perturbation | 0.74 | ||
protein domain | 0.73 | ||
transcription factor binding site profile | 0.73 | ||
transcription factor | 0.7 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.57 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 111 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.57 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 111 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (49)
LIG1
Family: Enzyme
Novelty: 0.00326816
p_int: 0.999998636
p_ni: 0.000001297
p_wrong: 6.7e-8
Score: 0.34
Data Source: BioPlex,STRINGDB
TNKS2
Family: Enzyme
Novelty: 0.00938509
p_int: 0.999997572
p_ni: 0.000002428
Data Source: BioPlex
TNKS
Family: Enzyme
Novelty: 0.00404545
p_int: 0.999990241
p_ni: 0.000009759
Data Source: BioPlex
TNFAIP6
Novelty: 0.0046811
p_int: 0.999921137
p_ni: 0.000039366
p_wrong: 0.000039497
Data Source: BioPlex
PARP11
Family: Enzyme
Novelty: 0.11901686
p_int: 0.999890182
p_ni: 0.000107041
p_wrong: 0.000002777
Score: 0.787
Data Source: BioPlex,STRINGDB
MPDZ
Novelty: 0.01656439
p_int: 0.999769557
p_ni: 0.000230443
Score: 0.189
Data Source: BioPlex,STRINGDB
PARP12
Family: Enzyme
Novelty: 0.08076657
p_int: 0.999684542
p_ni: 0.00022912
p_wrong: 0.000086338
Score: 0.538
Data Source: BioPlex,STRINGDB
NF2
Novelty: 0.00055092
p_int: 0.999555445
p_ni: 0.000444555
Score: 0.343
Data Source: BioPlex,STRINGDB
TNFAIP3
Novelty: 0.00257088
p_int: 0.999545963
p_ni: 0.000304585
p_wrong: 0.000149452
Score: 0.173
Data Source: BioPlex,STRINGDB
KIF1A
Novelty: 0.00505209
p_int: 0.999343176
p_ni: 0.000656796
p_wrong: 2.8e-8
Score: 0.173
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (1)
Functions (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (29)
Items per page:
1 – 5 of 29
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hemoglobin measurement | 5 | 9 | 10 | 99.3 | |||||
HbA1c measurement | 6 | 10 | 11 | 98.8 | |||||
mean corpuscular hemoglobin concentration | 7 | 5 | 9 | 98.2 | |||||
reticulocyte count | 6 | 10 | 18 | 97.8 | |||||
hematocrit | 4 | 6 | 7 | 97.4 | |||||
Items per page:
1 – 5 of 29
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hemoglobin measurement | 10 | 99.3 | |||||
HbA1c measurement | 11 | 98.8 | |||||
mean corpuscular hemoglobin concentration | 9 | 98.2 | |||||
reticulocyte count | 18 | 97.8 | |||||
hematocrit | 7 | 97.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ring finger protein 166 | VGNC:5910 | 468071 | |||||
Macaque | ring finger protein 166 | 711056 | ||||||
Mouse | MGI:1915968 | 68718 | ||||||
Rat | RGD:1302950 | 365022 | ||||||
Dog | ring finger protein 166 | VGNC:45642 | 608926 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ring finger protein 166 | |||||
Macaque | ring finger protein 166 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ring finger protein 166 | |||||
Publication Statistics
PubMed Score 2.57
PubMed score by year
PubTator Score 0.64
PubTator score by year
Related Publications
Text Mined References (8)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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