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Tdark
REX1BD
Required for excision 1-B domain-containing protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358607
  • ENSP00000351422
  • ENSG00000006015
  • ENST00000450195
  • ENSP00000398467

Symbol
  • C19orf60
  • C19orf60
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 7   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.69   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 7   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
PSMD7
Tbio
Family:  Enzyme
Novelty:  0.03090292
p_int:  0.999999999
p_wrong:  1e-9
Score:  0.234
Data Source:  BioPlex,STRINGDB
PSMD13
Tbio
Family:  Enzyme
Novelty:  0.04204417
p_int:  0.948369686
p_ni:  1.1e-8
p_wrong:  0.051630303
Data Source:  BioPlex
CRLF1
Tbio
Novelty:  0.02127014
Score:  0.804
Data Source:  STRINGDB
SMIM7
Tdark
Novelty:  0.71875113
Score:  0.672
Data Source:  STRINGDB
ANKRD35
Tdark
Novelty:  0.48931139
Score:  0.64
Data Source:  STRINGDB
MINDY1
Tbio
Novelty:  0.31540765
Score:  0.577
Data Source:  STRINGDB
CLCF1
Tbio
Novelty:  0.03134749
Score:  0.572
Data Source:  STRINGDB
RPL26L1
Tdark
Novelty:  0.75408617
Score:  0.536
Data Source:  STRINGDB
FAM53C
Tdark
Novelty:  1.18764113
Score:  0.532
Data Source:  STRINGDB
KBTBD2
Tdark
Novelty:  0.50755656
Score:  0.521
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Oral ulcer
1
1
0
1.1
73
blood metabolite measurement
1
1
1
60.2
reticulocyte measurement
1
1
1
55.2
mean corpuscular hemoglobin concentration
1
1
1
50.4
potassium measurement
1
1
1
38.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Oral ulcer
0
1.1
73
blood metabolite measurement
1
60.2
reticulocyte measurement
1
55.2
mean corpuscular hemoglobin concentration
1
50.4
potassium measurement
1
38.2
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
required for excision 1-B domain containing
VGNC:3652
735541
Macaque
required for excision 1-B domain containing
719555
Mouse
MGI:1913712
66462
Dog
required for excision 1-B domain containing
VGNC:45489
609827
Horse
required for excision 1-B domain containing
VGNC:22315
100071014
Species
Name
OMA
EggNOG
Inparanoid
Chimp
required for excision 1-B domain containing
Macaque
required for excision 1-B domain containing
Mouse
Dog
required for excision 1-B domain containing
Horse
required for excision 1-B domain containing
Publication Statistics
PubMed Score 0.69
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title