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Tdark
C15orf41
Uncharacterized protein C15orf41

Protein Summary
Description
This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000338183
  • ENSP00000342433
  • ENSG00000186073
  • ENST00000437989
  • ENSP00000401362
  • ENST00000562877
  • ENSP00000457854
  • ENST00000566621
  • ENSP00000455397
  • ENST00000567389
  • ENSP00000456736
  • ENST00000643785
  • ENSP00000496696

Symbol
  • HH114
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.04   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 123   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.04   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (25)
1 – 10 of 25
ASF1A
Tchem
Novelty: 0.02930331
p_int: 0.999999996
p_ni: 1e-9
p_wrong: 3e-9
Score: 0.228
Data Source: BioPlex,STRINGDB
ASF1B
Tbio
Novelty: 0.1035797
p_int: 0.999999995
p_ni: 2e-9
p_wrong: 3e-9
Score: 0.186
Data Source: BioPlex,STRINGDB
ZNF609
Tdark
Novelty: 0.15306122
p_int: 0.996151769
p_ni: 0.00384621
p_wrong: 0.000002022
Data Source: BioPlex
HELZ
Tbio
Family: Enzyme
Novelty: 0.0263006
p_int: 0.984618768
p_ni: 0.015381232
Data Source: BioPlex
SPDL1
Tbio
Novelty: 0.02478116
p_int: 0.964215009
p_ni: 0.035784537
p_wrong: 4.54e-7
Data Source: BioPlex
DNAJC1
Tbio
Family: TF
Novelty: 0.11404732
p_int: 0.959158759
p_ni: 0.040839601
p_wrong: 0.00000164
Data Source: BioPlex
ATXN2
Tbio
Novelty: 0.00420999
p_int: 0.945185153
p_ni: 0.054814847
Data Source: BioPlex
ZNF703
Tbio
Novelty: 0.05197807
p_int: 0.855687036
p_ni: 0.131133043
p_wrong: 0.013179922
Score: 0.186
Data Source: BioPlex,STRINGDB
C1orf146
Tdark
Score: 0.767
Data Source: STRINGDB
CDAN1
Tbio
Novelty: 0.00149492
Score: 0.706
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.04

PubMed score by year
PubTator Score  3.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer