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Tbio
ZC3H4
Zinc finger CCCH domain-containing protein 4

Protein Summary
Description
This gene encodes a member of a family of CCCH (C-x8-C-x5-C-x3-H type) zinc finger domain-containing proteins. These zinc finger domains, which coordinate zinc finger binding and are characterized by three cysteine residues and one histidine residue, are nucleic acid-binding. Other family members are known to function in post-transcriptional regulation. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253048
  • ENSP00000253048
  • ENSG00000130749

Symbol
  • C19orf7
  • KIAA1064
  • C19orf7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.94
transcription factor binding site profile
0.79
cellular component
0.73
microRNA
0.71
cell line
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.92   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.92   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (108)
1 – 10 of 108
CAPN13
Tdark
Novelty:  0.27206398
p_int:  0.999997677
p_ni:  0.0000022
p_wrong:  1.23e-7
Score:  0.206
Data Source:  BioPlex,STRINGDB
ZFP41
Tdark
Family:  TF
Novelty:  3.33093006
p_int:  0.999997633
p_ni:  0.000002367
p_wrong:  1e-9
Data Source:  BioPlex
RSPH9
Tbio
Novelty:  0.08651313
p_int:  0.999975826
p_ni:  0.000018754
p_wrong:  0.00000542
Score:  0.527
Data Source:  BioPlex,STRINGDB
FURIN
Tchem
Family:  Enzyme
Novelty:  0.00055079
p_int:  0.999726741
p_ni:  0.000272185
p_wrong:  0.000001074
Data Source:  BioPlex
JMJD6
Tchem
Family:  Enzyme
Novelty:  0.00305479
p_int:  0.999298198
p_ni:  0.000701799
p_wrong:  3e-9
Data Source:  BioPlex
HTRA4
Tbio
Family:  Enzyme
Novelty:  0.09298487
p_int:  0.997230503
p_ni:  0.002618482
p_wrong:  0.000151015
Score:  0.255
Data Source:  BioPlex,STRINGDB
H1FNT
Tdark
Novelty:  0.05593238
p_int:  0.996331997
p_ni:  0.003094679
p_wrong:  0.000573323
Data Source:  BioPlex
PDGFB
Tbio
Novelty:  0.00080876
p_int:  0.984803783
p_ni:  0.013812442
p_wrong:  0.001383775
Data Source:  BioPlex
MRPS11
Tdark
Novelty:  0.29449255
p_int:  0.981974264
p_ni:  0.016311739
p_wrong:  0.001713997
Data Source:  BioPlex
CPSF2
Tbio
Novelty:  0.0510853
Score:  0.85
Data Source:  STRINGDB
Gene Ontology Terms (9)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (34)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
3
3
95.5
hematocrit
3
3
3
93.3
body mass index
12
5
17
93
hemoglobin measurement
3
3
3
92.2
leukocyte count
2
2
2
80.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
95.5
hematocrit
3
93.3
body mass index
17
93
hemoglobin measurement
3
92.2
leukocyte count
2
80.6
Find similar targets by:
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 4
VGNC:7618
468930
Macaque
zinc finger CCCH-type containing 4
717905
Mouse
MGI:2682314
330474
Rat
RGD:1596943
678741
Dog
zinc finger CCCH-type containing 4
VGNC:48559
612160
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 4
Macaque
zinc finger CCCH-type containing 4
Mouse
Rat
Dog
zinc finger CCCH-type containing 4
Publication Statistics
PubMed Score 7.92
PubMed score by year
PubTator Score 1.45
PubTator score by year