Protein Summary
Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis.
- ENST00000380031
- ENSP00000369370
- ENSG00000120160
- ENST00000380032
- ENSP00000369371
- ENST00000537675
- ENSP00000441630
- AFAF
- C9orf11
- AFAF
- SPACA8
- C9orf11
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell line | 0.82 | ||
kinase perturbation | 0.71 | ||
cellular component | 0.69 | ||
tissue | 0.46 | ||
gene perturbation | 0.44 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 28.12 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 21 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 28.12 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 21 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0