You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TMEM168
Transmembrane protein 168

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312814
  • ENSP00000323068
  • ENSG00000146802
  • ENST00000447395
  • ENSP00000410307
  • ENST00000454074
  • ENSP00000390696
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
transcription factor perturbation
0.8
transcription factor binding site profile
0.79
microRNA
0.73
cell line
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.04   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.04   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (29)
1 – 10 of 29
FAM174A
Tdark
Novelty:  0.30693139
p_int:  0.99999727
p_ni:  7.69e-7
p_wrong:  0.000001961
Score:  0.804
Data Source:  BioPlex,STRINGDB
ATP2B2
Tbio
Family:  Transporter
Novelty:  0.007782
p_int:  0.999981873
p_ni:  1.74e-7
p_wrong:  0.000017953
Score:  0.516
Data Source:  BioPlex,STRINGDB
OLFML1
Tdark
Novelty:  0.27791923
Score:  0.775
Data Source:  STRINGDB
CCDC70
Tdark
Novelty:  0.79824592
Score:  0.647
Data Source:  STRINGDB
BMT2
Tbio
Family:  Enzyme
Novelty:  0.05916379
Score:  0.623
Data Source:  STRINGDB
ARHGAP20
Tbio
Family:  Enzyme
Novelty:  0.16551888
Score:  0.587
Data Source:  STRINGDB
ARMCX2
Tbio
Novelty:  0.09904258
Score:  0.585
Data Source:  STRINGDB
TMEM63B
Tdark
Family:  IC
Novelty:  0.25017412
Score:  0.576
Data Source:  STRINGDB
IFI27L2
Tdark
Novelty:  0.54359735
Score:  0.565
Data Source:  STRINGDB
ADNP2
Tdark
Novelty:  0.22823287
Score:  0.549
Data Source:  STRINGDB
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
LIFEdb
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 168
100612800
Macaque
transmembrane protein 168
702972
Mouse
MGI:1921794
101118
Rat
RGD:1307778
312135
Dog
transmembrane protein 168
VGNC:47495
100856171
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 168
Macaque
transmembrane protein 168
Mouse
Rat
Dog
transmembrane protein 168
Publication Statistics
PubMed Score 3.04
PubMed score by year
PubTator Score 0.25
PubTator score by year