You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
RAB5IF
Uncharacterized protein RAB5IF

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000342422
  • ENSP00000341213
  • ENSG00000101084
  • ENST00000344795
  • ENSP00000340164
  • ENST00000373852
  • ENSP00000362958
  • ENST00000483815
  • ENSP00000432510
  • ENST00000492721
  • ENSP00000435871

Symbol
  • C20orf24
  • RIP5
  • PNAS-11
  • C20orf24
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.53   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 29   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.53   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 29   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
1
1
1
75.9
1
1
0
1.3
71.8
1
1
0
1.3
49.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
1
75.9
0
1.3
71.8
0
1.3
49.4
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1914638
67388
Rat
RGD:1307752
296315
Dog
chromosome 24 C20orf24 homolog
485858
Horse
uncharacterized protein C20orf24 homolog
100147598
Cow
RAB5-interacting protein
512377
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
chromosome 24 C20orf24 homolog
Horse
uncharacterized protein C20orf24 homolog
Cow
RAB5-interacting protein
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BUV8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (22)
1 – 10 of 22
PDCD1
Tclin
Novelty: 0.000448
p_int: 0.999980455
p_ni: 0.000019543
p_wrong: 2e-9
Data Source: BioPlex
TMEM51
Tdark
Novelty: 0.54147214
p_int: 0.999874488
p_ni: 0.000088524
p_wrong: 0.000036988
Score: 0.213
Data Source: BioPlex,STRINGDB
CMKLR1
Tchem
Family: GPCR
Novelty: 0.00893083
p_int: 0.999638048
p_ni: 0.000202924
p_wrong: 0.000159028
Data Source: BioPlex
SLC22A9
Tbio
Family: Transporter
Novelty: 0.02212992
p_int: 0.999391603
p_ni: 0.000588036
p_wrong: 0.000020361
Data Source: BioPlex
TPST2
Tbio
Family: Enzyme
Novelty: 0.02551048
p_int: 0.999154265
p_ni: 0.00001372
p_wrong: 0.000832015
Data Source: BioPlex
SPINT2
Tbio
Family: Enzyme
Novelty: 0.0046602
p_int: 0.860277434
p_ni: 0.0000907
p_wrong: 0.139631867
Data Source: BioPlex
SLCO1B1
Tchem
Family: Transporter
Novelty: 0.00126613
p_int: 0.773164281
p_ni: 0.000037051
p_wrong: 0.226798668
Score: 0.223
Data Source: BioPlex,STRINGDB
MRGBP
Tbio
Novelty: 0.09537142
Score: 0.633
Data Source: STRINGDB
NOC4L
Tdark
Novelty: 0.39929311
Score: 0.58
Data Source: STRINGDB
SRPRB
Tbio
Novelty: 0.04735362
Score: 0.557
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.53

PubMed score by year
PubTator Score  0.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer