You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TSPAN18
Tetraspanin-18

Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.3
81
intraocular pressure measurement
1
1
1
25.9
brain measurement
1
1
0
274.1
6.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
81
intraocular pressure measurement
1
25.9
brain measurement
0
274.1
6.7
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tetraspanin 18
VGNC:12764
451141
Macaque
tetraspanin 18
715506
Mouse
MGI:1917186
241556
Rat
RGD:1560411
311210
Dog
tetraspanin 18
VGNC:47917
611375
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tetraspanin 18
Macaque
tetraspanin 18
Mouse
Rat
Dog
tetraspanin 18
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96SJ8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (19)
1 – 10 of 19
FITM2
Tdark
Novelty: 0.01882177
p_int: 0.862410462
p_ni: 0.073356583
p_wrong: 0.064232955
Score: 0.303
Data Source: BioPlex,STRINGDB
GHITM
Tbio
Novelty: 0.00360652
Score: 0.651
Data Source: STRINGDB
PICK1
Tbio
Novelty: 0.0058265
Score: 0.608
Data Source: STRINGDB
TSPAN32
Tbio
Novelty: 0.08323845
Score: 0.591
Data Source: STRINGDB
NKAPL
Tbio
Novelty: 0.24172313
Score: 0.589
Data Source: STRINGDB
ZSCAN31
Tdark
Family: TF
Novelty: 0.24834253
Score: 0.556
Data Source: STRINGDB
ZKSCAN4
Tbio
Family: TF
Novelty: 0.33154485
Score: 0.537
Data Source: STRINGDB
RNF130
Tdark
Family: Enzyme
Novelty: 0.26931521
Score: 0.527
Data Source: STRINGDB
TSPAN19
Tdark
Novelty: 0.92458543
Score: 0.476
Data Source: STRINGDB
CD300LG
Tbio
Novelty: 0.12664188
Score: 0.461
Data Source: STRINGDB
Publication Statistics
PubMed Score  14.37

PubMed score by year
PubTator Score  6.55

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer