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Tbio
ZNF582
Zinc finger protein 582

Protein Summary
Description
May be involved in transcriptional regulation. The protein encoded by this gene is a zing finger protein and putative transcription factor that is highly methylated in cervical cancers. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301310
  • ENSP00000301310
  • ENSG00000018869
  • ENST00000586929
  • ENSP00000465619
  • ENST00000619584
  • ENSP00000483414
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.69
microRNA
0.65
cell type or tissue
0.59
protein domain
0.58
tissue sample
0.53


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.61   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.61   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

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Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (10)
1 – 10 of 10
NECTIN4
Tclin
Novelty: 0.00694563
p_int: 0.999374056
p_ni: 0.000625943
p_wrong: 1e-9
Score: 0.403
Data Source: BioPlex,STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.925
Data Source: STRINGDB
PAX1
Tbio
Family: TF
Novelty: 0.00618274
Score: 0.71
Data Source: STRINGDB
SOX1
Tbio
Family: TF
Novelty: 0.0045679
Score: 0.6
Data Source: STRINGDB
PTPRR
Tbio
Family: Enzyme
Novelty: 0.02065754
Score: 0.538
Data Source: STRINGDB
TSTD1
Tdark
Family: Enzyme
Novelty: 0.49753107
Score: 0.473
Data Source: STRINGDB
PCDHA13
Tdark
Novelty: 1.14537708
Score: 0.446
Data Source: STRINGDB
DBNDD2
Tdark
Novelty: 0.46397269
Score: 0.446
Data Source: STRINGDB
NKX6-1
Tbio
Family: TF
Novelty: 0.00776559
Score: 0.414
Data Source: STRINGDB
FAM19A4
Tbio
Novelty: 0.04305684
Score: 0.4
Data Source: STRINGDB
Publication Statistics
PubMed Score  13.61

PubMed score by year
PubTator Score  7.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer