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Tbio
FUBP3
Far upstream element-binding protein 3

Protein Classes
Protein Summary
Description
May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319725
  • ENSP00000318177
  • ENSG00000107164

Symbol
  • FBP3
  • FBP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.97
histone modification site profile
0.91
transcription factor binding site profile
0.89
molecular function
0.84
kinase perturbation
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.72   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 262   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.72   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 262   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
1
1
1
92.5
femoral neck bone mineral density
2
2
2
87.6
body height
3
2
3
84.3
bone density
3
2
4
82.3
bone fracture
1
1
0
1
78.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
1
92.5
femoral neck bone mineral density
2
87.6
body height
3
84.3
bone density
4
82.3
bone fracture
0
1
78.3
Protein-Protein Interactions (55)
1 – 10 of 55
KLHL18
Tdark
Novelty: 0.52915213
p_int: 0.999474833
p_ni: 0.000525128
p_wrong: 3.9e-8
Data Source: BioPlex
PUF60
Tbio
Novelty: 0.02667356
Score: 0.926
Data Source: STRINGDB
FUBP1
Tbio
Novelty: 0.01745195
Score: 0.896
Data Source: STRINGDB
NQO1
Tchem
Family: Enzyme
Novelty: 0.00055755
Score: 0.866
Data Source: STRINGDB
PCBP2
Tbio
Novelty: 0.00826649
Score: 0.83
Data Source: STRINGDB
QKI
Tbio
Novelty: 0.00966983
Score: 0.828
Data Source: STRINGDB
ARF4
Tbio
Family: Enzyme
Novelty: 0.01166211
Score: 0.816
Data Source: STRINGDB
HNRNPF
Tbio
Novelty: 0.01833966
Score: 0.814
Data Source: STRINGDB
KHDRBS3
Tbio
Novelty: 0.00490069
Score: 0.693
Data Source: STRINGDB
DAZAP1
Tbio
Novelty: 0.04307077
Score: 0.616
Data Source: STRINGDB
Publication Statistics
PubMed Score  24.72

PubMed score by year
PubTator Score  17.34

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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