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Tbio
CCDC47
Coiled-coil domain-containing protein 47

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000225726
  • ENSP00000225726
  • ENSG00000108588
  • ENST00000403162
  • ENSP00000384888
  • ENST00000582252
  • ENSP00000463577

Symbol
  • THNS
  • GK001
  • MSTP041
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
kinase perturbation
0.88
transcription factor binding site profile
0.86
virus perturbation
0.79
microRNA
0.78


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.45   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 149   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.45   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 149   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
1
1
52
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
52
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 47
VGNC:12042
739076
Macaque
coiled-coil domain containing 47
717944
Mouse
MGI:1914413
67163
Rat
RGD:1308813
303606
Dog
coiled-coil domain containing 47
VGNC:51936
480480
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 47
Macaque
coiled-coil domain containing 47
Mouse
Rat
Dog
coiled-coil domain containing 47
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96A33-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (12)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (35)
1 – 10 of 35
SARM1
Tbio
Novelty: 0.00510488
Score: 0.789
Data Source: STRINGDB
TCP11L1
Tdark
Novelty: 1.5011461
Score: 0.75
Data Source: STRINGDB
SCYL1
Tbio
Family: Kinase
Novelty: 0.03774351
Score: 0.743
Data Source: STRINGDB
KIAA1211L
Tdark
Novelty: 1.5913836
Score: 0.74
Data Source: STRINGDB
IRAK1
Tchem
Family: Kinase
Novelty: 0.00170873
Score: 0.725
Data Source: STRINGDB
C1QL4
Tdark
Novelty: 0.37071722
Score: 0.641
Data Source: STRINGDB
MAN1A2
Tbio
Family: Enzyme
Novelty: 0.15637608
Score: 0.631
Data Source: STRINGDB
CLMP
Tbio
Novelty: 0.01435374
Score: 0.578
Data Source: STRINGDB
STRN3
Tbio
Novelty: 0.10331283
Score: 0.53
Data Source: STRINGDB
TMEM173
Tchem
Novelty: 0.0070581
Score: 0.53
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.45

PubMed score by year
PubTator Score  2.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer