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Tbio
TEKT4
Tektin-4

Protein Summary
Description
May be a structural component of the sperm flagellum. Contributes to normal sperm motility.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295201
  • ENSP00000295201
  • ENSG00000163060
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.6
gene perturbation
0.56
cellular component
0.53
cell line
0.47
cell type or tissue
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.35   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.35   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (38)
1 – 10 of 38
NEK1
Tchem
Family: Kinase
Novelty: 0.0164923
p_int: 0.999999299
p_ni: 7.01e-7
Score: 0.218
Data Source: BioPlex,STRINGDB
CRY1
Tchem
Novelty: 0.00116593
p_int: 0.999990895
p_ni: 0.000009105
Score: 0.552
Data Source: BioPlex,STRINGDB
CRY2
Tbio
Novelty: 0.00156961
p_int: 0.99998127
p_ni: 0.000018725
p_wrong: 5e-9
Score: 0.71
Data Source: BioPlex,STRINGDB
CFAP410
Tbio
Novelty: 0.0143773
p_int: 0.999924815
p_ni: 0.000075134
p_wrong: 5.2e-8
Score: 0.239
Data Source: BioPlex,STRINGDB
CLOCK
Tbio
Family: TF; Epigenetic
Novelty: 0.00159625
p_int: 0.999683425
p_ni: 0.000249772
p_wrong: 0.000066803
Score: 0.211
Data Source: BioPlex,STRINGDB
COG2
Tbio
Novelty: 0.03109287
p_int: 0.997124696
p_ni: 0.002875304
Score: 0.175
Data Source: BioPlex,STRINGDB
ABRAXAS1
Tbio
Novelty: 0.07078408
p_int: 0.995758664
p_ni: 0.000045505
p_wrong: 0.004195832
Score: 0.188
Data Source: BioPlex,STRINGDB
ADSL
Tbio
Family: Enzyme
Novelty: 0.0028496
p_int: 0.979724116
p_ni: 0.020275881
p_wrong: 3e-9
Score: 0.204
Data Source: BioPlex,STRINGDB
NDE1
Tbio
Novelty: 0.00567438
p_int: 0.905395316
p_ni: 0.094604684
Score: 0.196
Data Source: BioPlex,STRINGDB
COG4
Tbio
Novelty: 0.03809668
p_int: 0.807822839
p_ni: 0.192177161
Score: 0.177
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  18.35

PubMed score by year
PubTator Score  6.93

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer