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Tdark
ICA1L
Islet cell autoantigen 1-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358299
  • ENSP00000351047
  • ENSG00000163596
  • ENST00000392237
  • ENSP00000376070
  • ENST00000425178
  • ENSP00000404189
  • ENST00000617388
  • ENSP00000478645

Symbol
  • ALS2CR14
  • ALS2CR15
  • ALS2CR14
  • ALS2CR15
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
gene perturbation
0.76
microRNA
0.76
protein domain
0.73
tissue
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.63   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.63   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
2
2
79.9
heel bone mineral density
2
2
2
75
smoking status measurement
1
1
1
69
urinary albumin to creatinine ratio
3
1
3
64.8
albuminuria
1
1
1
45.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
79.9
heel bone mineral density
2
75
smoking status measurement
1
69
urinary albumin to creatinine ratio
3
64.8
albuminuria
1
45.4
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
islet cell autoantigen 1 like
VGNC:10845
459887
Macaque
islet cell autoantigen 1 like
704305
Mouse
MGI:1917625
70375
Rat
RGD:735110
316432
Dog
islet cell autoantigen 1 like
VGNC:41855
488479
Species
Name
OMA
EggNOG
Inparanoid
Chimp
islet cell autoantigen 1 like
Macaque
islet cell autoantigen 1 like
Mouse
Rat
Dog
islet cell autoantigen 1 like
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (65)
1 – 10 of 65
PICK1
Tbio
Novelty: 0.0058265
p_int: 0.999999956
p_ni: 5e-9
p_wrong: 3.9e-8
Score: 0.812
Data Source: BioPlex,STRINGDB
C8orf44
Tdark
Novelty: 4.22913257
Score: 0.765
Data Source: STRINGDB
CYP20A1
Tbio
Novelty: 0.11080329
Score: 0.763
Data Source: STRINGDB
GK5
Tbio
Family: Kinase
Novelty: 0.06110952
Score: 0.734
Data Source: STRINGDB
OPA3
Tbio
Novelty: 0.01508376
Score: 0.73
Data Source: STRINGDB
SRPK3
Tchem
Family: Kinase
Novelty: 0.16639453
Score: 0.692
Data Source: STRINGDB
PRR11
Tbio
Novelty: 0.05077483
Score: 0.683
Data Source: STRINGDB
JAKMIP3
Tdark
Family: Enzyme
Novelty: 0.52944633
Score: 0.611
Data Source: STRINGDB
OR2L13
Tdark
Family: oGPCR
Novelty: 0.3071575
Score: 0.602
Data Source: STRINGDB
SGSM1
Tbio
Novelty: 0.27948733
Score: 0.583
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.63

PubMed score by year
PubTator Score  0.1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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