You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ANKMY2
Ankyrin repeat and MYND domain-containing protein 2

Protein Summary
Description
May be involved in the trafficking of signaling proteins to the cilia.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306999
  • ENSP00000303570
  • ENSG00000106524

Symbol
  • ZMYND20
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
transcription factor binding site profile
0.83
disease perturbation
0.74
kinase perturbation
0.71
virus perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.1   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 150   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.1   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 150   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (64)
1 – 10 of 64
GUCY1B1
Tclin
Family:  Enzyme
Novelty:  0.03618378
p_int:  0.999999964
p_ni:  3.6e-8
Score:  0.665
Data Source:  BioPlex,STRINGDB
KANSL3
Tbio
Novelty:  0.00150009
p_int:  0.999996665
p_ni:  0.000003335
Score:  0.199
Data Source:  BioPlex,STRINGDB
ADCY3
Tbio
Family:  Enzyme
Novelty:  0.00260265
p_int:  0.999995141
p_ni:  0.000004859
Score:  0.232
Data Source:  BioPlex,STRINGDB
HSP90AB3P
Tdark
p_int:  0.999989635
p_ni:  0.000010361
p_wrong:  4e-9
Data Source:  BioPlex
ADCY9
Tbio
Family:  Enzyme
Novelty:  0.00744116
p_int:  0.999979597
p_ni:  0.000020403
Data Source:  BioPlex
GADL1
Tbio
Family:  Enzyme
Novelty:  0.018813
p_int:  0.999868711
p_ni:  0.000131289
Data Source:  BioPlex
SNX4
Tbio
Novelty:  0.05441145
p_int:  0.999731179
p_ni:  0.000268821
Score:  0.233
Data Source:  BioPlex,STRINGDB
AGO4
Tbio
Novelty:  0.00468833
p_int:  0.998539718
p_ni:  1.1e-8
p_wrong:  0.001460272
Score:  0.484
Data Source:  BioPlex,STRINGDB
PTGES3
Tbio
Family:  Enzyme
Novelty:  0.0082783
p_int:  0.996647055
p_ni:  0.003352945
Score:  0.39
Data Source:  BioPlex,STRINGDB
ADCY6
Tchem
Family:  Enzyme
Novelty:  0.00528765
p_int:  0.996465395
p_ni:  0.003534427
p_wrong:  1.78e-7
Score:  0.242
Data Source:  BioPlex,STRINGDB
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
3
3
93.6
reticulocyte count
7
2
13
89.8
reticulocyte measurement
3
2
6
89.3
red blood cell distribution width
2
1
2
65.6
mean corpuscular hemoglobin concentration
1
1
1
59.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
93.6
reticulocyte count
13
89.8
reticulocyte measurement
6
89.3
red blood cell distribution width
2
65.6
mean corpuscular hemoglobin concentration
1
59.9
Find similar targets by:
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat and MYND domain containing 2
VGNC:4259
463275
Macaque
ankyrin repeat and MYND domain containing 2
709414
Mouse
MGI:2144755
217473
Rat
RGD:1306017
314046
Dog
ankyrin repeat and MYND domain containing 2
VGNC:37878
100856722
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ankyrin repeat and MYND domain containing 2
Macaque
ankyrin repeat and MYND domain containing 2
Mouse
Rat
Dog
ankyrin repeat and MYND domain containing 2
Publication Statistics
PubMed Score 3.10
PubMed score by year
PubTator Score 0.09
PubTator score by year