Protein Summary
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).
- ENST00000612535
- ENSP00000477504
- ENSG00000271605
- ENST00000615220
- ENSP00000480749
- ENST00000616498
- ENSP00000481318
- ENST00000619286
- ENSP00000482801
- C17orf60
- MCA32
- MCA32
- MCA-32
- C17orf60
- Allergin-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.85 | ||
tissue | 0.83 | ||
cellular component | 0.62 | ||
tissue sample | 0.59 | ||
chemical | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 20.64 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 95 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 20.64 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 95 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0