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Tdark
CCDC121
Coiled-coil domain-containing protein 121

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.37   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.37   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (33)
1 – 10 of 33
LTBR
Tbio
Novelty: 0.00438925
p_int: 0.999999888
p_ni: 1e-9
p_wrong: 1.11e-7
Data Source: BioPlex
TBC1D17
Tdark
Novelty: 0.77348066
p_int: 0.999719465
p_ni: 0.000275433
p_wrong: 0.000005102
Score: 0.855
Data Source: BioPlex,STRINGDB
TBC1D15
Tbio
Novelty: 0.2389305
p_int: 0.984746168
p_ni: 0.015253832
Score: 0.665
Data Source: BioPlex,STRINGDB
UBE2E3
Tbio
Novelty: 0.0573923
p_int: 0.962301292
p_ni: 0.030577543
p_wrong: 0.007121165
Score: 0.228
Data Source: BioPlex,STRINGDB
SCRN1
Tbio
Family: Enzyme
Novelty: 0.11072976
p_int: 0.893074247
p_ni: 0.106925752
Score: 0.241
Data Source: BioPlex,STRINGDB
C2orf16
Tdark
Score: 0.732
Data Source: STRINGDB
ZNF512
Tbio
Family: TF
Novelty: 0.19294377
Score: 0.707
Data Source: STRINGDB
SUPT7L
Tdark
Novelty: 0.28836251
Score: 0.694
Data Source: STRINGDB
GPN1
Tbio
Family: Enzyme
Novelty: 0.08558329
Score: 0.656
Data Source: STRINGDB
GTF3C2
Tdark
Novelty: 0.29005525
Score: 0.633
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.37

PubMed score by year
PubTator Score  0.03

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer