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Tbio
TSHZ1
Teashirt homolog 1

Protein Summary
Description
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322038
  • ENSP00000323584
  • ENSG00000179981
  • ENST00000580243
  • ENSP00000464391

Symbol
  • SDCCAG33
  • TSH1
  • CAA
  • TSH1
  • NY-CO-33
  • SDCCAG33
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.81
transcription factor binding site profile
0.81
transcription factor perturbation
0.8
cell type or tissue
0.79
PubMedID
0.78


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.98   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 163   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.98   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 163   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure
1
1
1
5.5
1
1
1
5.4
1
1
0
1.3
1.9
1
1
0
1.3
1.9
prostate carcinoma
1
1
0
1.1
0.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
systolic blood pressure
1
5.5
1
5.4
0
1.3
1.9
0
1.3
1.9
prostate carcinoma
0
1.1
0.5
Gene Ontology Terms (10)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (54)
1 – 10 of 54
GLYAT
Tbio
Family: Enzyme
Novelty: 0.02347543
Score: 0.86
Data Source: STRINGDB
GAA
Tclin
Family: Enzyme
Novelty: 0.0063246
Score: 0.86
Data Source: STRINGDB
GGCT
Tchem
Family: Enzyme
Novelty: 0.01154389
Score: 0.839
Data Source: STRINGDB
AGA
Tbio
Family: Enzyme
Novelty: 0.01522819
Score: 0.837
Data Source: STRINGDB
GUCY2C
Tclin
Family: Kinase
Novelty: 0.00209733
Score: 0.837
Data Source: STRINGDB
GCA
Tbio
Novelty: 0.01485875
Score: 0.836
Data Source: STRINGDB
FLVCR2
Tbio
Novelty: 0.02871146
Score: 0.817
Data Source: STRINGDB
DOCK11
Tdark
Novelty: 0.0295159
Score: 0.8
Data Source: STRINGDB
MPG
Tchem
Family: Enzyme
Novelty: 0.00373538
Score: 0.797
Data Source: STRINGDB
PCYT1A
Tbio
Family: Enzyme
Novelty: 0.00621528
Score: 0.796
Data Source: STRINGDB
Publication Statistics
PubMed Score  45.98

PubMed score by year
PubTator Score  90.16

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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