Protein Summary
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012]
- ENST00000322038
- ENSP00000323584
- ENSG00000179981
- ENST00000580243
- ENSP00000464391
- SDCCAG33
- TSH1
- CAA
- TSH1
- NY-CO-33
- SDCCAG33
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.81 | ||
transcription factor binding site profile | 0.81 | ||
transcription factor perturbation | 0.8 | ||
cell type or tissue | 0.79 | ||
PubMedID | 0.78 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 132.68 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 163 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 132.68 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 163 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0