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Tdark
BHLHB9
Protein BHLHb9

Protein Summary
Description
May play a role in the control of cellular aging and survival. This gene is a member of a gene family which encodes proteins with a basic helix-loop-helix domain. Other members of this gene family encode proteins which function as transcription factors, either enhancing or inhibiting transcription depending on the activity of other DNA binding proteins. The coding region of this gene is located entirely within the terminal exon. The encoded protein may be involved in the survival of neurons (PMID: 15034937). Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361229
  • ENSP00000354675
  • ENSG00000198908
  • ENST00000372735
  • ENSP00000361820
  • ENST00000447531
  • ENSP00000405893
  • ENST00000448867
  • ENSP00000391722
  • ENST00000457056
  • ENSP00000403226

Symbol
  • KIAA1701
  • GASP3
  • p60TRP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
virus perturbation
0.72
tissue sample
0.68
small molecule perturbation
0.59
histone modification site profile
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.53   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.53   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0