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Tdark
BICRAL
BRD4-interacting chromatin-remodeling complex-associated protein-like

Protein Summary
Description
Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314073
  • ENSP00000313933
  • ENSG00000112624
  • ENST00000394168
  • ENSP00000377723
  • ENST00000614467
  • ENSP00000482211

Symbol
  • GLTSCR1L
  • KIAA0240
  • GLTSCR1L
  • KIAA0240
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein A 1 measurement
2
2
2
84.9
apolipoprotein B measurement
2
2
2
76.4
high density lipoprotein cholesterol measurement
2
2
3
74.4
homocysteine measurement
1
1
1
47.7
body mass index
1
1
1
46.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein A 1 measurement
2
84.9
apolipoprotein B measurement
2
76.4
high density lipoprotein cholesterol measurement
3
74.4
homocysteine measurement
1
47.7
body mass index
1
46.5
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
BRD4 interacting chromatin remodeling complex associated protein like
VGNC:2845
472008
Macaque
BRD4 interacting chromatin remodeling complex associated protein like
698668
Mouse
MGI:2673855
210982
Rat
RGD:1305680
301235
Dog
BRD4 interacting chromatin remodeling complex associated protein like
VGNC:38455
474904
Species
Name
OMA
EggNOG
Inparanoid
Chimp
BRD4 interacting chromatin remodeling complex associated protein like
Macaque
BRD4 interacting chromatin remodeling complex associated protein like
Mouse
Rat
Dog
BRD4 interacting chromatin remodeling complex associated protein like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6AI39-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (7)
1 – 7 of 7
BCL7C
Tdark
Novelty:  0.31203802
p_int:  0.999999854
p_ni:  1.46e-7
Score:  0.741
Data Source:  BioPlex,STRINGDB
SMARCD1
Tbio
Novelty:  0.03176642
p_int:  0.999998464
p_ni:  0.000001512
p_wrong:  2.5e-8
Score:  0.678
Data Source:  BioPlex,STRINGDB
BCL7A
Tbio
Novelty:  0.07026394
p_int:  0.99999842
p_ni:  0.00000156
p_wrong:  2e-8
Score:  0.707
Data Source:  BioPlex,STRINGDB
KCNJ14
Tchem
Family:  IC
Novelty:  0.05707639
Score:  0.506
Data Source:  STRINGDB
PHF12
Tbio
Family:  Epigenetic
Novelty:  0.00240295
Score:  0.47
Data Source:  STRINGDB
SGF29
Tbio
Family:  Epigenetic
Novelty:  0.0426456
Score:  0.458
Data Source:  STRINGDB
BRD9
Tchem
Family:  Epigenetic
Novelty:  0.03450227
Score:  0.426
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.47

PubMed score by year
PubTator Score  0.07

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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