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Tdark
TIMM23B
Putative mitochondrial import inner membrane translocase subunit Tim23B

Protein Summary
Description
May participate in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. the PAM complex (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374097
  • ENSP00000363210
  • ENSG00000204152
  • ENST00000374098
  • ENSP00000363211
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.56
cellular component
0.53
tissue sample
0.49
cell line
0.46
tissue
0.4


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.61   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 10   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.61   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 10   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
42.3
mean reticulocyte volume
1
1
1
36.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
42.3
mean reticulocyte volume
1
36.5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5SRD1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (100)
1 – 10 of 100
TIMM17B
Tdark
Family:  Enzyme
Novelty:  0.03556998
Score:  0.997
Data Source:  STRINGDB
TIMM17A
Tbio
Family:  Enzyme
Novelty:  0.02095904
Score:  0.995
Data Source:  STRINGDB
TIMM8A
Tbio
Family:  Enzyme
Novelty:  0.00954602
Score:  0.942
Data Source:  STRINGDB
TOMM22
Tbio
Novelty:  0.01217913
Score:  0.931
Data Source:  STRINGDB
TIMM13
Tdark
Family:  Enzyme
Novelty:  0.04802297
Score:  0.929
Data Source:  STRINGDB
TOMM20
Tbio
Novelty:  0.00275824
Score:  0.92
Data Source:  STRINGDB
TIMM22
Tbio
Family:  Enzyme
Novelty:  0.12627933
Score:  0.908
Data Source:  STRINGDB
TIMM50
Tbio
Family:  Enzyme
Novelty:  0.0238053
Score:  0.907
Data Source:  STRINGDB
TIMM10
Tbio
Family:  Enzyme
Novelty:  0.02727463
Score:  0.859
Data Source:  STRINGDB
TOMM40
Tbio
Novelty:  0.0041507
Score:  0.858
Data Source:  STRINGDB
Publication Statistics
PubMed Score  3.61

PubMed score by year
PubTator Score  0.2

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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