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Tdark
FAM214A
Protein FAM214A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261844
  • ENSP00000261844
  • ENSG00000047346
  • ENST00000534964
  • ENSP00000444447
  • ENST00000546305
  • ENSP00000443598
  • ENST00000619572
  • ENSP00000484641

Symbol
  • KIAA1370
  • KIAA1370
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.78
virus perturbation
0.76
cellular component
0.73
tissue
0.72
tissue sample
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 21   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 21   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
1
4
78
C-reactive protein measurement
1
1
1
68.6
2
2
1
1.1
53.6
lifestyle measurement
1
1
1
38.8
high density lipoprotein cholesterol measurement
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
78
C-reactive protein measurement
1
68.6
1
1.1
53.6
lifestyle measurement
1
38.8
high density lipoprotein cholesterol measurement
1
17.8
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 214 member A
VGNC:3558
453446
Macaque
family with sequence similarity 214 member A
696389
Mouse
MGI:2387648
235493
Rat
RGD:1310552
300836
Dog
family with sequence similarity 214 member A
VGNC:40662
487557
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 214 member A
Macaque
family with sequence similarity 214 member A
Mouse
Rat
Dog
family with sequence similarity 214 member A
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q32MH5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (31)
1 – 10 of 31
ARPP19
Tbio
Novelty:  0.03109958
Score:  0.773
Data Source:  STRINGDB
WDR45B
Tbio
Novelty:  0.22407227
Score:  0.772
Data Source:  STRINGDB
FAM227B
Tdark
Novelty:  9
Score:  0.737
Data Source:  STRINGDB
GLCCI1
Tbio
Novelty:  0.03220482
Score:  0.729
Data Source:  STRINGDB
LYSMD2
Tdark
Novelty:  3.17245408
Score:  0.684
Data Source:  STRINGDB
INTS1
Tbio
Novelty:  0.17523407
Score:  0.664
Data Source:  STRINGDB
RAB40B
Tbio
Novelty:  0.2288213
Score:  0.657
Data Source:  STRINGDB
WASHC4
Tdark
Novelty:  0.05930527
Score:  0.613
Data Source:  STRINGDB
FAM234B
Tdark
Novelty:  1.53957047
Score:  0.598
Data Source:  STRINGDB
ZNF280D
Tdark
Family:  TF
Novelty:  1.31551539
Score:  0.585
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.21

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer