Protein Summary
This gene encodes a cell cycle regulatory protein which plays an important role in cell cycle progression by binding and activating cyclin-dependent kinases. The encoded protein belongs to a family of cyclin-dependent kinase regulators that contain a speedy box domain which is required for cyclin-dependent kinase activation. [provided by RefSeq, Jul 2017]
- ENST00000563237
- ENSP00000485230
- ENSG00000260097
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
microRNA | 0.93 | ||
tissue sample | 0.73 | ||
tissue | 0.41 | ||
cell line | 0.35 | ||
transcription factor | 0.16 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.02 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 0 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.02 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 0 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0