Protein Summary
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
- ENST00000272641
- ENSP00000272641
- ENSG00000144227
- NPH2
- NPH2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.83 | ||
gene perturbation | 0.68 | ||
trait | 0.61 | ||
histone modification site profile | 0.54 | ||
disease | 0.5 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.92 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 90 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.92 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 90 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (49)
EEF1A2
Novelty: 0.001472
p_int: 0.999805808
p_ni: 0.000194192
Score: 0.152
Data Source: BioPlex,STRINGDB
ADGRV1
Family: GPCR
Novelty: 0.01398129
p_int: 0.997571795
p_ni: 0.002428205
Score: 0.158
Data Source: BioPlex,STRINGDB
MADD
Family: Enzyme
Novelty: 0.01590443
p_int: 0.997157935
p_ni: 0.002842064
p_wrong: 1e-9
Score: 0.179
Data Source: BioPlex,STRINGDB
PCDH7
Novelty: 0.04017185
p_int: 0.978281926
p_ni: 0.021718074
Score: 0.333
Data Source: BioPlex,STRINGDB
HBA1
Novelty: 0.00094113
p_int: 0.949717707
p_ni: 0.049195988
p_wrong: 0.001086304
Data Source: BioPlex
NRP2
Novelty: 0.00764179
p_int: 0.945280178
p_ni: 0.052367715
p_wrong: 0.002352108
Data Source: BioPlex
TAF7
Novelty: 0.05316615
p_int: 0.931079781
p_ni: 0.068920219
p_wrong: 1e-9
Score: 0.227
Data Source: BioPlex,STRINGDB
CELSR2
Family: GPCR
Novelty: 0.02657319
p_int: 0.914468167
p_ni: 0.085531833
Score: 0.166
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (3)
Functions (1)
Components (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
pregnancy induced alloimmunization | 1 | 1 | 0 | 2 | 21.5 | ||||
self reported educational attainment | 1 | 1 | 1 | 0.7 | |||||
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
pregnancy induced alloimmunization | 0 | 2 | 21.5 | ||||
self reported educational attainment | 1 | 0.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | neurexophilin 2 | VGNC:14325 | 742551 | |||||
Macaque | neurexophilin 2 | 704413 | ||||||
Mouse | MGI:107491 | 18232 | ||||||
Rat | RGD:1598138 | 679932 | ||||||
Dog | neurexophilin 2 | VGNC:44078 | 102154650 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | neurexophilin 2 | |||||
Macaque | neurexophilin 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | neurexophilin 2 | |||||
Publication Statistics
PubMed Score 1.92
PubMed score by year
PubTator Score 33.21
PubTator score by year
Related Publications
Text Mined References (8)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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