Protein Summary
- ENST00000510661
- ENSP00000424079
- ENSG00000204131
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.68 | ||
tissue sample | 0.66 | ||
cell type or tissue | 0.62 | ||
histone modification site profile | 0.62 | ||
chemical | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.13 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 14 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.13 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 14 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (34)
BRK1
Novelty: 0.02289534
p_int: 0.999996903
p_ni: 0.000003075
p_wrong: 2.3e-8
Score: 0.426
Data Source: BioPlex,STRINGDB
FGFR1OP2
Novelty: 0.1082136
p_int: 0.999842325
p_ni: 0.000148962
p_wrong: 0.000008713
Score: 0.165
Data Source: BioPlex,STRINGDB
ABI2
Novelty: 0.02324355
p_int: 0.999826629
p_ni: 0.000173371
Score: 0.632
Data Source: BioPlex,STRINGDB
WASF1
Novelty: 0.00977488
p_int: 0.999705866
p_ni: 0.00029304
p_wrong: 0.000001094
Score: 0.663
Data Source: BioPlex,STRINGDB
ABI1
Novelty: 0.00796638
p_int: 0.999274579
p_ni: 0.000725358
p_wrong: 6.3e-8
Score: 0.633
Data Source: BioPlex,STRINGDB
NCKAP1
Novelty: 0.03486454
p_int: 0.998977769
p_ni: 0.001022232
Score: 0.676
Data Source: BioPlex,STRINGDB
CYFIP2
Novelty: 0.01910939
p_int: 0.998577212
p_ni: 0.001422788
Score: 0.799
Data Source: BioPlex,STRINGDB
WASF2
Novelty: 0.00968798
p_int: 0.99839334
p_ni: 0.001606658
p_wrong: 2e-9
Score: 0.708
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (1)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (3)
Items per page:
1 – 3 of 3
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
testosterone measurement | 2 | 2 | 2 | 54.3 | |||||
platelet crit | 1 | 1 | 1 | 35 | |||||
platelet count | 1 | 1 | 1 | 30.2 | |||||
Items per page:
1 – 3 of 3
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
testosterone measurement | 2 | 54.3 | |||||
platelet crit | 1 | 35 | |||||
platelet count | 1 | 30.2 | |||||
Find similar targets by:
IDG Resources
Orthologs (4)
1 – 4 of 4
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:3645090 | 100042480 | ||||||
Dog | NHS like 2 | VGNC:43806 | 491954 | |||||
Cow | NHS like 2 | VGNC:32073 | 513680 | |||||
Anole lizard | NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Dog | NHS like 2 | |||||
Cow | NHS like 2 | |||||
Anole lizard | NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737] | |||||
Publication Statistics
PubMed Score 0.13
PubMed score by year
PubTator Score 0.20
PubTator score by year
Related Publications
Text Mined References (3)
Items per page:
0 of 0
PMID | Year | Title |
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