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Tbio
NECAB1
N-terminal EF-hand calcium-binding protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000417640
  • ENSP00000387380
  • ENSG00000123119
  • ENST00000521366
  • ENSP00000428632
  • ENST00000522820
  • ENSP00000428953

Symbol
  • EFCBP1
  • EFCBP1
  • STIP-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.93
protein domain
0.73
microRNA
0.65
histone modification site profile
0.63
cell line
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.54   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 182   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.54   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 182   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
NECAB3
Tbio
Novelty:  0.07893798
p_int:  0.999999973
p_ni:  2.5e-8
p_wrong:  2e-9
Score:  0.816
Data Source:  BioPlex,STRINGDB
NECAB2
Tbio
Novelty:  0.16192956
p_int:  0.999997703
p_ni:  0.000002264
p_wrong:  3.3e-8
Score:  0.738
Data Source:  BioPlex,STRINGDB
UTP4
Tbio
Novelty:  0.06989008
p_int:  0.999991596
p_ni:  0.000008404
Score:  0.157
Data Source:  BioPlex,STRINGDB
IP6K3
Tbio
Family:  Kinase
Novelty:  0.13072912
p_int:  0.999957139
p_ni:  0.000042861
Score:  0.25
Data Source:  BioPlex,STRINGDB
KANSL2
Tbio
Novelty:  0.08741608
p_int:  0.999158882
p_ni:  0.00084111
p_wrong:  8e-9
Score:  0.188
Data Source:  BioPlex,STRINGDB
MPRIP
Tbio
Family:  Enzyme
Novelty:  0.03253403
p_int:  0.997547668
p_ni:  0.002451219
p_wrong:  0.000001113
Score:  0.177
Data Source:  BioPlex,STRINGDB
RNF138
Tbio
Family:  TF
Novelty:  0.07543428
p_int:  0.994589482
p_ni:  0.005408492
p_wrong:  0.000002026
Score:  0.185
Data Source:  BioPlex,STRINGDB
MCRS1
Tbio
Novelty:  0.03404119
p_int:  0.987748663
p_ni:  0.012251334
p_wrong:  3e-9
Score:  0.177
Data Source:  BioPlex,STRINGDB
CCDC6
Tbio
Novelty:  0.00702098
p_int:  0.908014789
p_ni:  0.091985211
Data Source:  BioPlex
RAI14
Tbio
Novelty:  0.06291577
p_int:  0.792451112
p_ni:  0.206844488
p_wrong:  0.0007044
Score:  0.163
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
24.5
age at first sexual intercourse measurement
1
1
1
24.5
smoking behaviour measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
24.5
age at first sexual intercourse measurement
1
24.5
smoking behaviour measurement
1
24.5
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
N-terminal EF-hand calcium binding protein 1
VGNC:1162
472815
Macaque
N-terminal EF-hand calcium binding protein 1
696533
Mouse
MGI:1916602
69352
Rat
RGD:708548
64169
Dog
N-terminal EF-hand calcium binding protein 1
VGNC:43714
611356
Species
Name
OMA
EggNOG
Inparanoid
Chimp
N-terminal EF-hand calcium binding protein 1
Macaque
N-terminal EF-hand calcium binding protein 1
Mouse
Rat
Dog
N-terminal EF-hand calcium binding protein 1
Publication Statistics
PubMed Score 5.54
PubMed score by year
PubTator Score 1.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title