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Tdark
MAGEE2
Melanoma-associated antigen E2

Protein Summary
Description
This gene encodes a member of the E subfamily of MAGE (melanoma antigen-encoding gene) gene family. The gene is intronless and the encoded protein has two of the MAGE domains which are characteristic of MAGE family proteins. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373359
  • ENSP00000362457
  • ENSG00000186675

Symbol
  • HCA3
  • HCA3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.73
cell line
0.5
tissue
0.5
PubMedID
0.44
virus perturbation
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.3   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.3   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
ARIH1
Tbio
Family:  Enzyme
Novelty:  0.0258739
p_int:  0.98765216
p_ni:  0.01234784
Score:  0.187
Data Source:  BioPlex,STRINGDB
PLD6
Tbio
Family:  Enzyme
Novelty:  0.02802141
p_int:  0.792303988
p_ni:  0.002408047
p_wrong:  0.205287965
Score:  0.3
Data Source:  BioPlex,STRINGDB
GTPBP6
Tdark
Novelty:  0.05036884
Score:  0.726
Data Source:  STRINGDB
UBOX5
Tbio
Novelty:  0.37436118
Score:  0.638
Data Source:  STRINGDB
RNF166
Tdark
Novelty:  0.71460884
Score:  0.625
Data Source:  STRINGDB
NWD1
Tdark
Novelty:  0.28220226
Score:  0.615
Data Source:  STRINGDB
PUS7L
Tdark
Family:  Enzyme
Novelty:  0.96856727
Score:  0.595
Data Source:  STRINGDB
ZNF416
Tdark
Family:  TF
Novelty:  0.8335845
Score:  0.58
Data Source:  STRINGDB
TENT5D
Tbio
Novelty:  0.1864027
Score:  0.572
Data Source:  STRINGDB
CSAG1
Tbio
Novelty:  0.16422262
Score:  0.565
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
MAGE family member E2
704907
Mouse
MGI:2148316
272790
Rat
RGD:1564872
302392
Dog
MAGE family member E2
VGNC:42925
480961
Cow
MAGE family member E2
VGNC:31144
525318
Species
Name
OMA
EggNOG
Inparanoid
Macaque
MAGE family member E2
Mouse
Rat
Dog
MAGE family member E2
Cow
MAGE family member E2
Publication Statistics
PubMed Score 2.30
PubMed score by year
PubTator Score 4.35
PubTator score by year
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Related Publications
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PMID
Year
Title