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Tdark
LYZL2
Lysozyme-like protein 2

Protein Summary
Description
Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL2 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375318
  • ENSP00000364467
  • ENSG00000151033
  • ENST00000647634
  • ENSP00000497408

Symbol
  • LYZD2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
metabolite
0.45
phenotype
0.36
disease
0.35
biological term
0.33


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.41   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 41   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.41   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
GALNT18
Tbio
Family:  Enzyme
Novelty:  0.15496205
p_int:  0.999921102
p_ni:  0.000078897
p_wrong:  1e-9
Data Source:  BioPlex
ENTPD5
Tbio
Family:  Enzyme
Novelty:  0.01714402
p_int:  0.99985106
p_ni:  0.000037241
p_wrong:  0.0001117
Score:  0.179
Data Source:  BioPlex,STRINGDB
LOXL2
Tchem
Family:  Enzyme
Novelty:  0.00599536
p_int:  0.999467121
p_ni:  0.000532867
p_wrong:  1.2e-8
Data Source:  BioPlex
B4GALNT4
Tdark
Family:  Enzyme
Novelty:  0.19278471
p_int:  0.998772617
p_ni:  0.000704747
p_wrong:  0.000522636
Data Source:  BioPlex
COL6A2
Tbio
Novelty:  0.01275082
p_int:  0.99838354
p_ni:  0.00161646
Data Source:  BioPlex
FKBP14
Tbio
Family:  Enzyme
Novelty:  0.02742616
p_int:  0.998146972
p_ni:  0.001822831
p_wrong:  0.000030197
Data Source:  BioPlex
SULF1
Tbio
Family:  Enzyme
Novelty:  0.00992209
p_int:  0.998016449
p_ni:  0.001506995
p_wrong:  0.000476556
Data Source:  BioPlex
VWDE
Tdark
Novelty:  0.37298162
p_int:  0.997705708
p_ni:  0.002283438
p_wrong:  0.000010854
Data Source:  BioPlex
PCYOX1L
Tdark
Family:  Enzyme
Novelty:  1.25398886
p_int:  0.997588425
p_ni:  0.002411556
p_wrong:  1.8e-8
Data Source:  BioPlex
TMEM67
Tbio
Novelty:  0.02573267
p_int:  0.997337728
p_ni:  0.002661085
p_wrong:  0.000001187
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-EC
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
1
1
26.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
26.1
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1914578
67328
Rat
RGD:1559869
364745
Dog
lysozyme-like protein 1
487083
Horse
lysozyme-like protein 1
100055156
Cow
lysozyme-like 1
512087
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
lysozyme-like protein 1
Horse
lysozyme-like protein 1
Cow
lysozyme-like 1
Publication Statistics
PubMed Score 1.41
PubMed score by year
PubTator Score 1.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title