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Tdark
KIAA2013
Uncharacterized protein KIAA2013

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376572
  • ENSP00000365756
  • ENSG00000116685
  • ENST00000376576
  • ENSP00000365760
  • ENST00000616327
  • ENSP00000480577
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.88
tissue sample
0.73
disease perturbation
0.68
transcription factor perturbation
0.68
transcription factor
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.85   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.85   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (56)
ATP6V0A2
Tbio
Family:  Enzyme
Novelty:  0.00504614
p_int:  0.999999903
p_ni:  9.7e-8
Score:  0.844
Data Source:  BioPlex,STRINGDB
VMA21
Tdark
Family:  Enzyme
Novelty:  0.46129032
p_int:  0.999990941
p_ni:  0.000006715
p_wrong:  0.000002344
Score:  0.851
Data Source:  BioPlex,STRINGDB
TMEM199
Tbio
Novelty:  0.05799147
p_int:  0.999939639
p_ni:  0.000060361
Score:  0.855
Data Source:  BioPlex,STRINGDB
CCDC115
Tbio
Novelty:  0.23966137
p_int:  0.999561302
p_ni:  0.000288367
p_wrong:  0.000150331
Score:  0.817
Data Source:  BioPlex,STRINGDB
ATP6V0A1
Tbio
Family:  Enzyme
Novelty:  0.02009317
p_int:  0.999221235
p_ni:  0.000778765
Score:  0.826
Data Source:  BioPlex,STRINGDB
ATP6V0C
Tbio
Family:  Enzyme
Novelty:  0.01142874
p_int:  0.998617099
p_ni:  0.001382798
p_wrong:  1.04e-7
Score:  0.831
Data Source:  BioPlex,STRINGDB
CLEC2B
Tbio
Novelty:  0.06581244
p_int:  0.993206282
p_ni:  0.006793718
Data Source:  BioPlex
ATP6AP2
Tbio
Novelty:  0.00357665
p_int:  0.992549104
p_ni:  0.007450896
Score:  0.826
Data Source:  BioPlex,STRINGDB
P2RY12
Tclin
Family:  GPCR
Novelty:  0.00035406
p_int:  0.991697785
p_ni:  0.008302215
Data Source:  BioPlex
CLDND1
Tbio
Novelty:  0.06681793
p_int:  0.989590669
p_ni:  0.010409331
Score:  0.158
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (26)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
4
4
3
2.2
97.7
NT-proBNP measurement
2
3
3
95.2
platelet crit
2
2
2
95
BNP measurement
2
2
2
88.1
blood protein measurement
1
2
2
81.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
2.2
97.7
NT-proBNP measurement
3
95.2
platelet crit
2
95
BNP measurement
2
88.1
blood protein measurement
2
81.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
KIAA2013
VGNC:6896
736680
Macaque
KIAA2013 ortholog
722762
Mouse
MGI:1924284
77034
Rat
RGD:1305350
313699
Dog
KIAA2013
VGNC:54759
478228
Species
Name
OMA
EggNOG
Inparanoid
Chimp
KIAA2013
Macaque
KIAA2013 ortholog
Mouse
Rat
Dog
KIAA2013
Publication Statistics
PubMed Score 1.85
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title