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Tbio
IGDCC4
Immunoglobulin superfamily DCC subclass member 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000352385
  • ENSP00000319623
  • ENSG00000103742

Symbol
  • DDM36
  • KIAA1628
  • NOPE
  • NOPE
  • DDM36
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
microRNA
0.76
protein domain
0.73
tissue sample
0.56
virus perturbation
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.42   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 54   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.42   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
TMEM30B
Tbio
Novelty:  0.26735006
p_int:  0.999998079
p_ni:  1.29e-7
p_wrong:  0.000001792
Score:  0.177
Data Source:  BioPlex,STRINGDB
RAET1E
Tbio
Novelty:  0.01859274
p_int:  0.955031674
p_ni:  0.000006179
p_wrong:  0.044962148
Score:  0.199
Data Source:  BioPlex,STRINGDB
FAM173B
Tbio
Novelty:  0.02367461
Score:  0.659
Data Source:  STRINGDB
GRAMD2A
Tbio
Novelty:  0.4291251
Score:  0.634
Data Source:  STRINGDB
NAPEPLD
Tbio
Family:  Enzyme
Novelty:  0.00755191
Score:  0.536
Data Source:  STRINGDB
TULP4
Tbio
Family:  TF
Novelty:  0.05658032
Score:  0.504
Data Source:  STRINGDB
IGSF11
Tbio
Novelty:  0.07516371
Score:  0.501
Data Source:  STRINGDB
DNAJA1
Tchem
Novelty:  0.00894126
Score:  0.499
Data Source:  STRINGDB
P4HA3
Tbio
Family:  Enzyme
Novelty:  0.03832564
Score:  0.482
Data Source:  STRINGDB
LENG8
Tdark
Novelty:  0.66682078
Score:  0.478
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
2
2
2
89.4
heel bone mineral density
2
2
3
88.5
mean reticulocyte volume
1
1
1
79.6
neutrophil count
1
1
1
69.8
monocyte percentage of leukocytes
1
1
1
64.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
2
89.4
heel bone mineral density
3
88.5
mean reticulocyte volume
1
79.6
neutrophil count
1
69.8
monocyte percentage of leukocytes
1
64.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin superfamily DCC subclass member 4
VGNC:10256
453517
Macaque
immunoglobulin superfamily DCC subclass member 4
713405
Mouse
MGI:1858497
56741
Rat
RGD:1310919
363081
Dog
immunoglobulin superfamily DCC subclass member 4
VGNC:41894
487604
Species
Name
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin superfamily DCC subclass member 4
Macaque
immunoglobulin superfamily DCC subclass member 4
Mouse
Rat
Dog
immunoglobulin superfamily DCC subclass member 4
Publication Statistics
PubMed Score 9.42
PubMed score by year
PubTator Score 1.86
PubTator score by year
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Related Publications
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PMID
Year
Title