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Tdark
TRIM77
Tripartite motif-containing protein 77

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398290
  • ENSP00000474003
  • ENSG00000214414

Symbol
  • TRIM77P
  • TRIM77P
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
cell line
0.7
tissue
0.49
protein complex
0.4
cellular component
0.37


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.04   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.04   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
1
1
1
79.5
1
1
0
1.6
1.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
1
79.5
0
1.6
1.7
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-I1YAP6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (7)
1 – 7 of 7
TRIM42
Tdark
Novelty:  0.21068414
Score:  0.638
Data Source:  STRINGDB
H1FOO
Tbio
Novelty:  0.02189067
Score:  0.523
Data Source:  STRINGDB
OOSP2
Tdark
Novelty:  0.90000132
Score:  0.523
Data Source:  STRINGDB
BMP15
Tbio
Novelty:  0.00364888
Score:  0.472
Data Source:  STRINGDB
TRIM59
Tbio
Novelty:  0.04240864
Score:  0.44
Data Source:  STRINGDB
TRIM56
Tbio
Family:  Enzyme
Novelty:  0.09343452
Score:  0.439
Data Source:  STRINGDB
TRIM14
Tbio
Novelty:  0.06156875
Score:  0.427
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.04

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer