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Tdark
HSP90AA4P
Putative heat shock protein HSP 90-alpha A4

Protein Summary
Description
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
Uniprot Accession IDs
Gene Name
Symbol
  • HSP90AD
  • HSPCAL2
  • HSP90Ad
  • HSPCAL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.61
tissue
0.56
cell line
0.43
cellular component
0.38
disease
0.27


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
PINK1
Tbio
Family:  Kinase
Novelty:  0.00100973
p_int:  0.999999938
p_ni:  6.1e-8
Data Source:  BioPlex
HSP90AB1
Tchem
Novelty:  0.00907961
p_int:  0.999999889
p_ni:  1.11e-7
Data Source:  BioPlex
AKT3
Tchem
Family:  Kinase
Novelty:  0.00308931
p_int:  0.999999593
p_ni:  4.07e-7
Data Source:  BioPlex
RPS6KA4
Tchem
Family:  Kinase
Novelty:  0.05213255
p_int:  0.999999338
p_ni:  6.62e-7
Data Source:  BioPlex
CDK9
Tchem
Family:  Kinase
Novelty:  0.00210218
p_int:  0.999999258
p_ni:  7.4e-7
p_wrong:  3e-9
Data Source:  BioPlex
MAP2K2
Tclin
Family:  Kinase
Novelty:  0.00706525
p_int:  0.999999217
p_ni:  7.77e-7
p_wrong:  6e-9
Data Source:  BioPlex
STK11
Tchem
Family:  Kinase
Novelty:  0.00073247
p_int:  0.999998158
p_ni:  0.000001822
p_wrong:  2e-8
Data Source:  BioPlex
CDK13
Tchem
Family:  Kinase
Novelty:  0.03084808
p_int:  0.999997737
p_ni:  0.000002232
p_wrong:  3.1e-8
Data Source:  BioPlex
CCDC117
Tdark
Novelty:  1.11966553
p_int:  0.999997694
p_ni:  0.000001895
p_wrong:  4.11e-7
Data Source:  BioPlex
AGO1
Tbio
Novelty:  0.00157424
p_int:  0.999996792
p_ni:  0.000003203
p_wrong:  5e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (18)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubTator Score 1.41
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title