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Tbio
GSTCD
Glutathione S-transferase C-terminal domain-containing protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360505
  • ENSP00000353695
  • ENSG00000138780
  • ENST00000394728
  • ENSP00000378216
  • ENST00000394730
  • ENSP00000378218
  • ENST00000515279
  • ENSP00000422354
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
kinase perturbation
0.76
transcription factor binding site profile
0.75
small molecule perturbation
0.63
cell line
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.18   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.18   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
MMP14
Tchem
Family:  Enzyme
Novelty:  0.00083836
p_int:  0.999999318
p_ni:  4.05e-7
p_wrong:  2.78e-7
Data Source:  BioPlex
PLA2G10
Tchem
Family:  Enzyme
Novelty:  0.00289317
p_int:  0.999996887
p_ni:  0.0000031
p_wrong:  1.2e-8
Data Source:  BioPlex
IFT20
Tbio
Novelty:  0.03005088
p_int:  0.999991849
p_ni:  0.000007315
p_wrong:  8.36e-7
Data Source:  BioPlex
KLRC4
Tbio
Novelty:  0.16922525
p_int:  0.9999852
p_ni:  0.000014362
p_wrong:  4.38e-7
Data Source:  BioPlex
C5AR2
Tbio
Family:  GPCR
Novelty:  0.01193736
p_int:  0.999982397
p_ni:  0.000016247
p_wrong:  0.000001356
Data Source:  BioPlex
FZD10
Tbio
Family:  GPCR
Novelty:  0.02786933
p_int:  0.999902658
p_ni:  0.000059762
p_wrong:  0.00003758
Score:  0.202
Data Source:  BioPlex,STRINGDB
PHF19
Tbio
Family:  Epigenetic
Novelty:  0.02289037
p_int:  0.999851308
p_ni:  0.000110507
p_wrong:  0.000038184
Score:  0.187
Data Source:  BioPlex,STRINGDB
INTS12
Tbio
Family:  Epigenetic
Novelty:  0.09023473
Score:  0.766
Data Source:  STRINGDB
THSD4
Tbio
Novelty:  0.12898073
Score:  0.719
Data Source:  STRINGDB
FAM13A
Tbio
Novelty:  0.02851485
Score:  0.71
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Metapathway biotransformation Phase I and II
WikiPathways
Metapathway biotransformation Phase I and II
WikiPathways
Metapathway biotransformation Phase I and II
WikiPathways
Metapathway biotransformation Phase I and II
WikiPathways
The alternative pathway of fetal androgen synthesis
Name
Explore in Pharos
Explore in Source
Metapathway biotransformation Phase I and II
Metapathway biotransformation Phase I and II
Metapathway biotransformation Phase I and II
Metapathway biotransformation Phase I and II
The alternative pathway of fetal androgen synthesis
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
forced expiratory volume
7
5
6
1.2
98.6
FEV/FEC ratio
2
3
3
97.7
2
3
0
1.2
95.4
peak expiratory flow
1
2
2
93
vital capacity
2
2
3
90.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
forced expiratory volume
6
1.2
98.6
FEV/FEC ratio
3
97.7
0
1.2
95.4
peak expiratory flow
2
93
vital capacity
3
90.6
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
glutathione S-transferase C-terminal domain containing
VGNC:6476
461419
Macaque
glutathione S-transferase C-terminal domain containing
694220
Mouse
MGI:1914803
67553
Rat
RGD:1311822
310855
Dog
glutathione S-transferase C-terminal domain containing
VGNC:41535
487890
Species
Name
OMA
EggNOG
Inparanoid
Chimp
glutathione S-transferase C-terminal domain containing
Macaque
glutathione S-transferase C-terminal domain containing
Mouse
Rat
Dog
glutathione S-transferase C-terminal domain containing
Publication Statistics
PubMed Score 9.18
PubMed score by year
PubTator Score 2.58
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title