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Tdark
GOT1L1
Putative aspartate aminotransferase, cytoplasmic 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307599
  • ENSP00000303077
  • ENSG00000169154
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
cell line
0.61
protein domain
0.58
metabolite
0.45
cellular component
0.44


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.77   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.77   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
SERPINA1
Tbio
Novelty:  0.00014098
p_int:  0.996449865
p_ni:  0.003527778
p_wrong:  0.000022357
Score:  0.207
Data Source:  BioPlex,STRINGDB
APOA1
Tbio
Novelty:  0.0001216
p_int:  0.979894155
p_ni:  0.020099999
p_wrong:  0.000005846
Score:  0.213
Data Source:  BioPlex,STRINGDB
GOT1
Tbio
Family:  Enzyme
Novelty:  0.00448817
p_int:  0.977495415
p_ni:  0.022504585
Score:  0.71
Data Source:  BioPlex,STRINGDB
PLPBP
Tbio
Family:  Enzyme
Novelty:  0.04352366
Score:  0.631
Data Source:  STRINGDB
LETM2
Tdark
Novelty:  0.23845199
Score:  0.594
Data Source:  STRINGDB
GLUD2
Tbio
Family:  Enzyme
Novelty:  0.01470266
Score:  0.558
Data Source:  STRINGDB
GLUD1
Tbio
Family:  Enzyme
Novelty:  0.00301109
Score:  0.558
Data Source:  STRINGDB
PLEKHA2
Tbio
Novelty:  0.14583759
Score:  0.555
Data Source:  STRINGDB
ERLIN2
Tbio
Novelty:  0.04060163
Score:  0.542
Data Source:  STRINGDB
GPT2
Tbio
Family:  Enzyme
Novelty:  0.00478585
Score:  0.536
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
PathwayCommons: humancyc
aspartate biosynthesis
PathwayCommons: humancyc
glutamate degradation II
PathwayCommons: humancyc
aspartate degradation II
Name
Explore in Pharos
Explore in Source
aspartate biosynthesis
glutamate degradation II
aspartate degradation II
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1923865
76615
Rat
RGD:1307172
306540
Horse
glutamic-oxaloacetic transaminase 1 like 1
VGNC:18466
100059580
Cow
glutamic-oxaloacetic transaminase 1 like 1
VGNC:29502
507913
Opossum
glutamic-oxaloacetic transaminase 1 like 1
100032942
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
glutamic-oxaloacetic transaminase 1 like 1
Cow
glutamic-oxaloacetic transaminase 1 like 1
Opossum
glutamic-oxaloacetic transaminase 1 like 1
Publication Statistics
PubMed Score 2.77
PubMed score by year
PubTator Score 1.33
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title