You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
GATD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319863
  • ENSP00000321691
  • ENSG00000177225
  • ENST00000354286
  • ENSP00000346239
  • ENST00000397472
  • ENSP00000380612
  • ENST00000524550
  • ENSP00000431183

Symbol
  • PDDC1
  • PDDC1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.37   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.37   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (62)
PREPL
Tchem
Family:  Enzyme
Novelty:  0.02310586
p_int:  0.999921792
p_ni:  0.000078208
Data Source:  BioPlex
HPS5
Tbio
Novelty:  0.05155851
p_int:  0.998392754
p_ni:  0.001604889
p_wrong:  0.000002357
Score:  0.186
Data Source:  BioPlex,STRINGDB
FAM19A3
Tdark
Novelty:  0.37183557
p_int:  0.998381551
p_ni:  0.001617157
p_wrong:  0.000001292
Data Source:  BioPlex
RTEL1
Tbio
Family:  Enzyme
Novelty:  0.00761538
p_int:  0.998269868
p_ni:  0.001730131
Data Source:  BioPlex
FMN2
Tbio
Novelty:  0.02031944
p_int:  0.995361969
p_ni:  0.004636237
p_wrong:  0.000001794
Data Source:  BioPlex
ITSN1
Tbio
Novelty:  0.01327346
p_int:  0.990616694
p_ni:  0.009383306
Data Source:  BioPlex
PER1
Tbio
Novelty:  0.01290576
p_int:  0.98520126
p_ni:  0.014798626
p_wrong:  1.14e-7
Data Source:  BioPlex
LSS
Tchem
Family:  Enzyme
Novelty:  0.00735187
p_int:  0.984286651
p_ni:  0.004821261
p_wrong:  0.010892088
Data Source:  BioPlex
TRIM65
Tbio
Novelty:  0.09830696
p_int:  0.982394485
p_ni:  0.017575326
p_wrong:  0.000030189
Data Source:  BioPlex
USP54
Tdark
Family:  Enzyme
Novelty:  0.31344498
p_int:  0.981359715
p_ni:  0.018640236
p_wrong:  5e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
3
5
6
91.5
mean platelet volume
2
2
2
89.4
intraocular pressure measurement
2
3
3
89
waist-hip ratio
4
6
9
86.9
2
2
1
6.6
82.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
6
91.5
mean platelet volume
2
89.4
intraocular pressure measurement
3
89
waist-hip ratio
9
86.9
1
6.6
82.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
glutamine amidotransferase like class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]
Mouse
MGI:2387178
213350
Rat
RGD:1304836
309110
Dog
Parkinson disease 7 domain containing 1
610760
Horse
glutamine amidotransferase like class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]
Species
Name
OMA
EggNOG
Inparanoid
Macaque
glutamine amidotransferase like class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]
Mouse
Rat
Dog
Parkinson disease 7 domain containing 1
Horse
glutamine amidotransferase like class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]
Publication Statistics
PubMed Score 2.37
PubMed score by year
Related Publications
No publications found