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Tdark
FRMD1
FERM domain-containing protein 1

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.66   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.66   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (101)
MUC7
Tbio
Novelty:  0.00750654
p_int:  0.999999451
p_ni:  5.47e-7
p_wrong:  2e-9
Data Source:  BioPlex
BPIFA2
Tbio
Novelty:  0.01533858
p_int:  0.999998947
p_ni:  0.000001052
p_wrong:  2e-9
Data Source:  BioPlex
MUC5B
Tbio
Novelty:  0.000832
p_int:  0.99999883
p_ni:  0.00000117
Data Source:  BioPlex
MPO
Tchem
Family:  Enzyme
Novelty:  0.00020698
p_int:  0.999997586
p_ni:  0.000001353
p_wrong:  0.000001061
Score:  0.256
Data Source:  BioPlex,STRINGDB
IGHA2
Tbio
p_int:  0.999996004
p_ni:  0.000003995
p_wrong:  2e-9
Data Source:  BioPlex
SCEL
Tbio
Novelty:  0.03037518
p_int:  0.999994325
p_ni:  0.000005464
p_wrong:  2.11e-7
Score:  0.226
Data Source:  BioPlex,STRINGDB
SPRR3
Tbio
Novelty:  0.0241484
p_int:  0.999991902
p_ni:  0.000008073
p_wrong:  2.5e-8
Score:  0.165
Data Source:  BioPlex,STRINGDB
PIGR
Tbio
Novelty:  0.0025812
p_int:  0.999947246
p_ni:  0.000052753
Data Source:  BioPlex
SKAP2
Tbio
Family:  Enzyme
Novelty:  0.00614207
p_int:  0.999941969
p_ni:  0.000058028
p_wrong:  2e-9
Data Source:  BioPlex
CRNN
Tbio
Novelty:  0.01648731
p_int:  0.999904864
p_ni:  0.000095136
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
3
4
93.6
red blood cell density measurement
1
1
1
60.2
1
1
0
11.4
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
4
93.6
red blood cell density measurement
1
60.2
0
11.4
15.8
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
FERM domain containing 1
VGNC:2835
740949
Macaque
FERM domain containing 1
694078
Cow
FERM domain containing 1
616869
Pig
FERM domain containing 1
100514201
Opossum
FERM domain containing 1
100032645
Species
Name
OMA
EggNOG
Inparanoid
Chimp
FERM domain containing 1
Macaque
FERM domain containing 1
Cow
FERM domain containing 1
Pig
FERM domain containing 1
Opossum
FERM domain containing 1
Publication Statistics
PubMed Score 0.66
PubMed score by year
PubTator Score 0.24
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title