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Tdark
FAM234B
Protein FAM234B

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.03   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 39   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.03   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 39   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (61)
DEPDC1
Tbio
Novelty:  0.04255829
p_int:  0.999997972
p_ni:  0.000002027
p_wrong:  1e-9
Data Source:  BioPlex
FRMD5
Tbio
Novelty:  0.34991399
p_int:  0.999994546
p_ni:  0.000005453
p_wrong:  1e-9
Score:  0.211
Data Source:  BioPlex,STRINGDB
SLC25A51
Tbio
Family:  Transporter
Novelty:  0.21568087
p_int:  0.999984161
p_ni:  0.000015839
Data Source:  BioPlex
TMEM214
Tdark
Novelty:  0.32604613
p_int:  0.999969248
p_ni:  0.000030752
Data Source:  BioPlex
HIP1R
Tbio
Novelty:  0.02502713
p_int:  0.999828481
p_ni:  0.000171519
Data Source:  BioPlex
NRSN2
Tbio
Novelty:  0.1812093
p_int:  0.999643654
p_ni:  0.000165682
p_wrong:  0.000190664
Score:  0.186
Data Source:  BioPlex,STRINGDB
TRIM13
Tbio
Family:  Enzyme
Novelty:  0.00085649
p_int:  0.99961909
p_ni:  0.000022823
p_wrong:  0.000358088
Data Source:  BioPlex
PEX11B
Tbio
Novelty:  0.04285427
p_int:  0.999549322
p_ni:  0.000036626
p_wrong:  0.000414052
Score:  0.177
Data Source:  BioPlex,STRINGDB
ORC5
Tbio
Novelty:  0.02264865
p_int:  0.996585675
p_ni:  0.003136246
p_wrong:  0.00027808
Data Source:  BioPlex
LEMD3
Tbio
Novelty:  0.00579701
p_int:  0.995912689
p_ni:  0.004087311
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
5
10
98
mean reticulocyte volume
1
1
1
70.8
mean corpuscular hemoglobin concentration
1
1
1
52.7
serum albumin measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
10
98
mean reticulocyte volume
1
70.8
mean corpuscular hemoglobin concentration
1
52.7
serum albumin measurement
1
24.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 234 member B
VGNC:5375
465301
Macaque
family with sequence similarity 234 member B
698063
Mouse
MGI:1921775
74525
Rat
RGD:1306151
362455
Dog
family with sequence similarity 234 member B
VGNC:40673
486678
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 234 member B
Macaque
family with sequence similarity 234 member B
Mouse
Rat
Dog
family with sequence similarity 234 member B
Publication Statistics
PubMed Score 1.03
PubMed score by year
PubTator Score 0.10
PubTator score by year
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Related Publications
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PMID
Year
Title