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Tdark
FAM193B
Protein FAM193B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000514747
  • ENSP00000422131
  • ENSG00000146067

Symbol
  • IRIZIO
  • KIAA1931
  • IRIZIO
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.74
tissue sample
0.6
histone modification site profile
0.56
transcription factor
0.55
virus perturbation
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.32   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.32   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
TRIM10
Tbio
Novelty:  0.27685659
p_int:  0.999999995
p_ni:  3e-9
p_wrong:  1e-9
Score:  0.39
Data Source:  BioPlex,STRINGDB
ERICH5
Tdark
Novelty:  5.57504212
Score:  0.793
Data Source:  STRINGDB
TMED9
Tbio
Novelty:  0.24024246
Score:  0.725
Data Source:  STRINGDB
LRRC45
Tdark
Novelty:  0.38407505
Score:  0.717
Data Source:  STRINGDB
HIBCH
Tbio
Family:  Enzyme
Novelty:  0.02964018
Score:  0.714
Data Source:  STRINGDB
PRR7
Tbio
Novelty:  0.08132975
Score:  0.698
Data Source:  STRINGDB
ASNSD1
Tdark
Family:  Enzyme
Novelty:  0.54006324
Score:  0.659
Data Source:  STRINGDB
ASDURF
Tdark
Novelty:  0.54006324
Score:  0.659
Data Source:  STRINGDB
PMS1
Tbio
Family:  TF
Novelty:  0.00444827
Score:  0.649
Data Source:  STRINGDB
ARMC8
Tbio
Novelty:  0.06820746
Score:  0.625
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
3
3
88.1
intelligence
3
3
1
6.1
84.1
mathematical ability
3
3
4
83.5
educational attainment
1
2
2
76.3
appendicular lean mass
1
1
1
59.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
3
88.1
intelligence
1
6.1
84.1
mathematical ability
4
83.5
educational attainment
2
76.3
appendicular lean mass
1
59.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 193 member B
VGNC:3993
462313
Mouse
MGI:2385851
212483
Rat
RGD:1562335
498703
Dog
family with sequence similarity 193 member B
VGNC:40642
479273
Horse
family with sequence similarity 193 member B [Source:HGNC Symbol;Acc:HGNC:25524]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 193 member B
Mouse
Rat
Dog
family with sequence similarity 193 member B
Horse
family with sequence similarity 193 member B [Source:HGNC Symbol;Acc:HGNC:25524]
Publication Statistics
PubMed Score 1.32
PubMed score by year
PubTator Score 0.40
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title