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Tdark
FAM187B
Protein FAM187B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324675
  • ENSP00000323355
  • ENSG00000177558

Symbol
  • TMEM162
  • TMEM162
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.56
trait
0.46
cell line
0.42
tissue
0.41
disease
0.38


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.34   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 40   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.34   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (34)
MOSPD2
Tbio
Novelty:  0.14602473
p_int:  0.99998349
p_ni:  0.00001651
Score:  0.175
Data Source:  BioPlex,STRINGDB
SOAT1
Tchem
Family:  Enzyme
Novelty:  0.00530755
p_int:  0.995721892
p_ni:  0.004278106
p_wrong:  2e-9
Score:  0.185
Data Source:  BioPlex,STRINGDB
SLC25A6
Tchem
Family:  Transporter
Novelty:  0.0052748
p_int:  0.975128989
p_ni:  0.024871011
Score:  0.204
Data Source:  BioPlex,STRINGDB
CANX
Tbio
Novelty:  0.00087002
p_int:  0.970122775
p_ni:  0.029877225
Data Source:  BioPlex
RPL23
Tbio
Novelty:  0.02741113
p_int:  0.95741539
p_ni:  0.04258461
Data Source:  BioPlex
TUBA1A
Tchem
Novelty:  0.01030145
p_int:  0.949460084
p_ni:  0.050539916
Data Source:  BioPlex
VRK2
Tbio
Family:  Kinase
Novelty:  0.03300582
p_int:  0.880563869
p_ni:  0.119436131
Score:  0.204
Data Source:  BioPlex,STRINGDB
HSPA5
Tchem
Novelty:  0.00043424
p_int:  0.873693012
p_ni:  0.126306988
Data Source:  BioPlex
SPPL2B
Tchem
Family:  Enzyme
Novelty:  0.0274774
p_int:  0.849929948
p_ni:  0.150070052
Data Source:  BioPlex
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.772348704
p_ni:  0.227651296
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
5
7
91.6
reticulocyte count
7
3
7
91.1
mean platelet volume
3
3
3
84.8
reticulocyte measurement
3
2
3
73.8
mean corpuscular hemoglobin concentration
1
1
1
63.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
7
91.6
reticulocyte count
7
91.1
mean platelet volume
3
84.8
reticulocyte measurement
3
73.8
mean corpuscular hemoglobin concentration
1
63.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 187 member B
VGNC:11010
468833
Macaque
family with sequence similarity 187, member B
707890
Mouse
MGI:1923665
76415
Dog
family with sequence similarity 187 member B
VGNC:40636
612665
Horse
family with sequence similarity 187 member B
VGNC:51025
100059149
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 187 member B
Macaque
family with sequence similarity 187, member B
Mouse
Dog
family with sequence similarity 187 member B
Horse
family with sequence similarity 187 member B
Publication Statistics
PubMed Score 1.34
PubMed score by year
PubTator Score 1.09
PubTator score by year
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Related Publications
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PMID
Year
Title