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Tdark
FAM133B
Protein FAM133B

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.74   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (20)
VPS50
Tbio
Novelty:  0.17236696
Score:  0.589
Data Source:  STRINGDB
RBM48
Tdark
Novelty:  0.50797247
Score:  0.589
Data Source:  STRINGDB
HEPACAM2
Tbio
Novelty:  0.19192547
Score:  0.582
Data Source:  STRINGDB
SAMD9L
Tbio
Novelty:  0.03957268
Score:  0.558
Data Source:  STRINGDB
STEAP1B
Tdark
Novelty:  0.76423576
Score:  0.54
Data Source:  STRINGDB
CEP85L
Tbio
Novelty:  0.23631446
Score:  0.535
Data Source:  STRINGDB
EFCAB1
Tdark
Novelty:  0.74253143
Score:  0.514
Data Source:  STRINGDB
ANKIB1
Tdark
Novelty:  0.47935971
Score:  0.508
Data Source:  STRINGDB
CCDC138
Tdark
Novelty:  4.02014418
Score:  0.495
Data Source:  STRINGDB
SAMD9
Tbio
Novelty:  0.02006718
Score:  0.477
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (43)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
6
4
5
5.8
99.3
BMI-adjusted hip circumference
3
19
24
96.2
heel bone mineral density
3
3
5
93.4
leukocyte count
2
4
4
89.4
BMI-adjusted waist circumference
3
3
5
87.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
5
5.8
99.3
BMI-adjusted hip circumference
24
96.2
heel bone mineral density
5
93.4
leukocyte count
4
89.4
BMI-adjusted waist circumference
5
87.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
family with sequence similarity 133 member B
702054
Mouse
MGI:1915402
68152
Rat
RGD:1306302
362320
Dog
family with sequence similarity 133 member B
VGNC:40593
100856224
Horse
family with sequence similarity 133 member B
VGNC:17802
100051070
Species
Name
OMA
EggNOG
Inparanoid
Macaque
family with sequence similarity 133 member B
Mouse
Rat
Dog
family with sequence similarity 133 member B
Horse
family with sequence similarity 133 member B
Publication Statistics
PubMed Score 1.74
PubMed score by year
PubTator Score 0.07
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title