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Tdark
FAM122B
Protein FAM122B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298090
  • ENSP00000298090
  • ENSG00000156504
  • ENST00000370790
  • ENSP00000359826
  • ENST00000486347
  • ENSP00000419592
  • ENST00000493333
  • ENSP00000487221

Symbol
  • SPACIA2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.81
transcription factor perturbation
0.74
tissue
0.59
transcription factor
0.53
cellular component
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.48   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.48   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
FHL3
Tbio
Novelty:  0.11505924
p_int:  0.999998456
p_ni:  0.000001544
Score:  0.337
Data Source:  BioPlex,STRINGDB
PPP2R2C
Tbio
Family:  Enzyme
Novelty:  0.05453128
p_int:  0.999994331
p_ni:  0.000005668
p_wrong:  1e-9
Score:  0.205
Data Source:  BioPlex,STRINGDB
PLOD1
Tbio
Family:  Enzyme
Novelty:  0.00905345
p_int:  0.999987249
p_ni:  0.000012722
p_wrong:  2.8e-8
Data Source:  BioPlex
ANKRD29
Tdark
Novelty:  1.29202649
p_int:  0.999986507
p_ni:  0.000013356
p_wrong:  1.37e-7
Score:  0.187
Data Source:  BioPlex,STRINGDB
WDR83
Tbio
Novelty:  0.11602568
p_int:  0.999970834
p_ni:  0.000029166
Data Source:  BioPlex
TUSC3
Tbio
Novelty:  0.01388722
p_int:  0.999915216
p_ni:  0.000080099
p_wrong:  0.000004684
Data Source:  BioPlex
FAM122A
Tbio
Novelty:  0.3107759
p_int:  0.999584399
p_ni:  0.000379569
p_wrong:  0.000036033
Score:  0.821
Data Source:  BioPlex,STRINGDB
IFI30
Tbio
Family:  Enzyme
Novelty:  0.00939681
p_int:  0.999242756
p_ni:  0.00075683
p_wrong:  4.14e-7
Data Source:  BioPlex
SPIN2B
Tchem
Novelty:  0.23202718
p_int:  0.998702669
p_ni:  0.001274493
p_wrong:  0.000022838
Data Source:  BioPlex
SCRN2
Tdark
Family:  Enzyme
Novelty:  1.63547022
p_int:  0.998634032
p_ni:  0.001335634
p_wrong:  0.000030333
Score:  0.19
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
birth weight
2
1
2
61
hematocrit
1
1
1
37.6
glomerular filtration rate
1
1
0
5.5
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
birth weight
2
61
hematocrit
1
37.6
glomerular filtration rate
0
5.5
14.2
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 122B
VGNC:3766
735824
Mouse
MGI:1926005
78755
Rat
RGD:6501955
100909732
Dog
family with sequence similarity 122B
VGNC:54140
492149
Horse
family with sequence similarity 122B
VGNC:49433
100054128
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 122B
Mouse
Rat
Dog
family with sequence similarity 122B
Horse
family with sequence similarity 122B
Publication Statistics
PubMed Score 0.48
PubMed score by year
PubTator Score 1.03
PubTator score by year
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Related Publications
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PMID
Year
Title