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Tbio
DNAJA4
DnaJ homolog subfamily A member 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000343789
  • ENSP00000339581
  • ENSG00000140403
  • ENST00000394852
  • ENSP00000378321
  • ENST00000394855
  • ENSP00000378324
  • ENST00000446172
  • ENSP00000413499

Symbol
  • MST104
  • MSTP104
  • PRO1472
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
molecular function
0.88
protein domain
0.85
small molecule perturbation
0.79
PubMedID
0.77


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.63   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 138   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.63   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 138   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (92)
HPSE
Tchem
Family:  Enzyme
Novelty:  0.00162921
p_int:  0.994876838
p_ni:  0.005123126
p_wrong:  3.6e-8
Score:  0.408
Data Source:  BioPlex,STRINGDB
MYORG
Tbio
Family:  Enzyme
Novelty:  0.0478246
p_int:  0.982166701
p_ni:  0.017129595
p_wrong:  0.000703704
Score:  0.302
Data Source:  BioPlex,STRINGDB
TCTN2
Tbio
Novelty:  0.11617528
p_int:  0.977917083
p_ni:  0.020722635
p_wrong:  0.001360282
Data Source:  BioPlex
PSCA
Tbio
Novelty:  0.00323778
p_int:  0.890792636
p_ni:  0.106350777
p_wrong:  0.002856587
Data Source:  BioPlex
EIF3I
Tbio
Novelty:  0.04398155
p_int:  0.773750851
p_ni:  0.226089642
p_wrong:  0.000159506
Score:  0.411
Data Source:  BioPlex,STRINGDB
HSPA8
Tchem
Novelty:  0.00081014
Score:  0.989
Data Source:  Reactome,STRINGDB
HSPA1A
Tchem
Novelty:  0.00069195
Score:  0.986
Data Source:  Reactome,STRINGDB
HSPA1L
Tbio
Novelty:  0.01658161
Score:  0.974
Data Source:  STRINGDB
HSPA1B
Tbio
Novelty:  0.01429214
Score:  0.974
Data Source:  Reactome,STRINGDB
HSPA2
Tchem
Novelty:  0.01696667
Score:  0.97
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Cellular responses to external stimuli (R-HSA-8953897)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cellular responses to external stimuli
Reactome
Cellular responses to stress
Reactome
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Name
Explore in Pharos
Explore in Source
Cellular responses to external stimuli
Cellular responses to stress
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
5
7
8
96.3
reticulocyte count
4
5
8
87.3
reticulocyte measurement
2
4
6
83.6
hematocrit
4
4
5
81.5
hemoglobin measurement
2
2
2
79.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
8
96.3
reticulocyte count
8
87.3
reticulocyte measurement
6
83.6
hematocrit
5
81.5
hemoglobin measurement
2
79.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DnaJ heat shock protein family (Hsp40) member A4
VGNC:6580
453567
Macaque
DnaJ heat shock protein family (Hsp40) member A4
709872
Mouse
MGI:1927638
58233
Rat
RGD:1310035
300721
Dog
DnaJ heat shock protein family (Hsp40) member A4
488777
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DnaJ heat shock protein family (Hsp40) member A4
Macaque
DnaJ heat shock protein family (Hsp40) member A4
Mouse
Rat
Dog
DnaJ heat shock protein family (Hsp40) member A4
Publication Statistics
PubMed Score 7.63
PubMed score by year
PubTator Score 3.24
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title