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Tdark
CCDC9
Coiled-coil domain-containing protein 9

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000221922
  • ENSP00000221922
  • ENSG00000105321
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.96
transcription factor binding site profile
0.74
transcription factor
0.73
cell type or tissue
0.61
tissue sample
0.6


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.26   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
CASC3
Tbio
Novelty:  0.03935581
p_int:  0.999985638
p_ni:  0.000014362
Data Source:  BioPlex
LUC7L2
Tdark
Novelty:  0.36989457
p_int:  0.999976794
p_ni:  0.000023205
p_wrong:  1e-9
Data Source:  BioPlex
PPP2R3B
Tbio
Family:  Enzyme
Novelty:  0.02932064
p_int:  0.999973041
p_ni:  0.000026958
p_wrong:  1e-9
Data Source:  BioPlex
PRPF40A
Tbio
Novelty:  0.00898047
p_int:  0.999947635
p_ni:  0.000052073
p_wrong:  2.92e-7
Score:  0.311
Data Source:  BioPlex,STRINGDB
SNIP1
Tbio
Novelty:  0.01865867
p_int:  0.999878075
p_ni:  0.00012192
p_wrong:  6e-9
Score:  0.505
Data Source:  BioPlex,STRINGDB
TBCCD1
Tbio
Novelty:  0.21991508
p_int:  0.999875436
p_ni:  0.000121672
p_wrong:  0.000002891
Data Source:  BioPlex
WSB2
Tbio
Novelty:  0.03939755
p_int:  0.999839621
p_ni:  0.000160379
Score:  0.558
Data Source:  BioPlex,STRINGDB
ZC3H14
Tbio
Novelty:  0.07532778
p_int:  0.999800645
p_ni:  0.000199339
p_wrong:  1.7e-8
Data Source:  BioPlex
SARNP
Tbio
Novelty:  0.00987312
p_int:  0.999776903
p_ni:  0.000223093
p_wrong:  4e-9
Score:  0.203
Data Source:  BioPlex,STRINGDB
NKAPD1
Tdark
Novelty:  1.56979675
p_int:  0.999634277
p_ni:  0.000365722
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
3
3
95.5
myeloid white cell count
1
1
1
75.7
appendicular lean mass
1
1
1
59.6
lymphocyte percentage of leukocytes
1
1
1
57.8
neutrophil percentage of leukocytes
1
1
1
53.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
95.5
myeloid white cell count
1
75.7
appendicular lean mass
1
59.6
lymphocyte percentage of leukocytes
1
57.8
neutrophil percentage of leukocytes
1
53.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 9
VGNC:3640
107969773
Macaque
coiled-coil domain containing 9
717144
Mouse
MGI:1921443
243846
Rat
RGD:1584422
684934
Horse
coiled-coil domain containing 9
VGNC:16188
100146412
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 9
Macaque
coiled-coil domain containing 9
Mouse
Rat
Horse
coiled-coil domain containing 9
Publication Statistics
PubMed Score 1.26
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title